Search for dissertations about: "β-1"

Showing result 1 - 5 of 30 swedish dissertations containing the word β-1.

  1. 1. Exploration of the active site of β4GalT7 – Synthesis of substrates and inhibitors

    Author : Karin Thorsheim; Centrum för analys och syntes; []
    Keywords : Xylosides; β4GalT7; β-1; 4-galactosyltransferase 7; glycosaminoglycan; synthesis;

    Abstract : β-1,4-Galactosyltransferase 7 (β4GalT7) is a key enzyme in the biosynthesis of proteoglycans (PGs) and glycosaminoglycan (GAG) chains, which are important macromolecules involved in many biological processes such as cell growth and cell signaling as well as in cancer pathobiology and viral and bacterial infections. Despite its pivotal role, much is still unknown regarding the specific structure of GAGs and how the structure affects its functions. READ MORE

  2. 2. Characterization of some molecules in the prophenoloxidase-activating and clotting systems in the freswater crayfish Pacifastacus leniusculus

    Author : Ruigong Wang; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; fysiologisk mykologi; Physiological Mycology;

    Abstract : A lipopolysaccharide- and β-1,3-glucan-binding protein (LGBP) was purified from crayfish hemocytes. LGBP has binding activity to lipopolysaccharide, curdlan (insoluble β-1,3-glucans) and laminarin (soluble β-1,3-glucans), but not to peptidoglycan. READ MORE

  3. 3. Innovative processing of brown seaweed for value-added products

    Author : Leila Allahgholi; Bioteknik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The increasing depletion of fossil fuels, rising greenhouse gas emissions, and a growing global population have increased the need for sustainable food and energy sources. Traditional industrial biotechnology, which relies on plant-based feedstocks, competes with food production for arable land. READ MORE

  4. 4. Structural and biochemical insights into biosynthesis and degradation of N-glycans

    Author : Tom Reichenbach; Christina Divne; David Drew; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; N-glycan; biosynthesis; degradation; glycosyltransferase; glycoside hydrolase; biofuel; enzyme; membrane protein; Bioteknologi; Biotechnology;

    Abstract : Carbohydrates are a primary energy source for all living organisms, but importantly, they also participate in a number of life-sustaining biological processes, e.g. cell signaling and cell-wall synthesis. The first part of the thesis examines glycosyltransferases that play a crucial role in the biosynthesis of N-glycans. READ MORE

  5. 5. Structural Studies of Three Glycosidases

    Author : Anna Larsson; Alwyn Jones; Janet Smith; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; glycosidase; dextranase; mannanase; endoglucanase; SeMet; MAD; crystal structure; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Glycosidases hydrolyse the glycosidic bond in carbohydrates. Structural studies of three glycosidases with different substrate specificities are presented in this work.Dextranase catalyzes the hydrolysis of α-1,6-glycosidic linkage in dextran polymers. READ MORE