Search for dissertations about: "δ-cell"
Found 4 swedish dissertations containing the word δ-cell.
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1. Studies of cAMP and Ca2+ signaling in pancreatic islet cells
Abstract : The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood. READ MORE
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2. α-Cell signalling in glucose-regulated glucagon secretion
Abstract : Glucagon is a blood glucose-elevating hormone released from α-cells in the islets of Langerhans during hypoglycaemia. Glucagon is critical for glucose homeostasis and inappropriate regulation of its secretion underlies both impaired counter-regulation of hypoglycaemia and chronic hyperglycaemia in diabetes patients. READ MORE
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3. Paracrine control of glucagon secretion in the pancreatic α-cell: Studies involving optogenetic cell activation
Abstract : ABSTRACT The mechanisms controlling glucagon secretion by α-cells in islets of Langerhans were studied. We generated mice with the light-activated ion channel ChR2 specifically expressed in β-, α-, and δ-cells, and explored the spatio-temporal relationship between cell activation and glucagon release. READ MORE
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4. Cell coupling and exocytosis measured in intact mouse pancreatic islets Control of {delta}-cell secretion
Abstract : Patch-clamp and capacitance measurements were applied to α-, β- and δ-cells in intact mouse pancreatic islets. The maximum rate of β-cell exocytosis during a depolarization to 0 mV was 14 granules/s, ... READ MORE