Search for dissertations about: "13-cis RA"

Found 1 swedish dissertation containing the words 13-cis RA.

2. 1. Retinoids in experimental neuroblastoma therapy

   Author : Frida Ponthan; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Vitamin A; retinoids; neuroblastoma; 9-cis RA; Ro 13-6307; differentiation; apoptosis; growth inhibition; 13-cis RA; fenretinide; proton magnetic resonance spectroscopy; pharmacokinetic.;

   Abstract : Retinoids are analogues of vitamin A, with documented activity against various malignant cell types. Neuroblastoma is a childhood tumour of the sympathetic nervous system that shows a complex clinical and biological heterogeneity, often with poor outcome despite intensive multimodal therapy. READ MORE