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Showing result 1 - 5 of 10 swedish dissertations matching the above criteria.

  1. 1. Structural and functional studies of biomolecules with NMR and CD spectroscopy

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Evangelos Papadopoulos; Stockholms universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR; protein structure; nouse Doppel; HTH; C-repressor; potassium channel; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : Experimentally derived biomolecular structures were determined by Nuclear Magnetic Resonance (NMR). The properties of selected peptides and proteins in solution and in membrane mimicking micelles were observed by circular Dichroism (CD), mass spectrometry (MS), and other spectroscopic techniques. READ MORE

  2. 2. Characterizing Chromatography Media NMR-based Approaches

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Fredrik Elwinger; KTH.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatography; nuclear magnetic resonance; NMR; self-diffusion; magic-angle spinning; quantitative; distribution coefficient; pore size; Kemi; Chemistry;

    Abstract : Liquid chromatography is an essential technique in manufacturing biopharmaceuticals where it is used on all scales from analytical applications in R&D to full-scale production. In chromatography the target molecule, typically a protein, is separated and purified from other components and contaminants. READ MORE

  3. 3. Mechanistic Studies of Organocopper Chemistry by NMR Spectroscopy: Conjugate Additions to Alkynes and Alkenes

    University dissertation from Chalmers University of Technology

    Author : Karolina Nilsson; Chalmers tekniska högskola.; Chalmers University of Technology.; [1997]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry; mechanism; conjugate addition; organocopper reagents; ynoates; ynones; enoates; pi-complexes; lithium dimethylcuprate; cyanocuprate; 13C and 15N NMR spectroscopy; 6Li; 1H-HOESY;

    Abstract : This thesis focuses on the mechanisms of organocopper reactions, in particular the reactions with activated alkynes (ynoates and ynones). These reactions are of interest in the formation of new highly functionalized double bonds with control of the stereochemistry. READ MORE

  4. 4. Structure and Dynamics of the Hepatitis B Virus Encapsidation Signal Revealed by NMR Spectroscopy

    University dissertation from Umeå : Medicinsk biokemi och biofysik

    Author : Sara Flodell; Umeå universitet.; [2004]
    Keywords : HBV; RNA; isotope labelling; NMR; structure determination; medicinsk biokemi; Medical Biochemistry;

    Abstract : This thesis describes the study of the three-dimensional structure and dynamics of the hepatitis B virus (HBV) encapsidation signal, epsilon, by means of nuclear magnetic resonance (NMR) and mutational data. HBV replicates by reverse transcription of an RNA pregenome into the viral DNA genome, which becomes enclosed in viral particles (encapsidation). READ MORE

  5. 5. Glutaredoxin 3 from Escherichia coli : NMR structure analysis and structural aspects of the enzymatic mechanism

    University dissertation from Stockholm : Karolinska Institutet, Department of Medical Biochemistry and Biophysics

    Author : Kerstin Nordstrand; Karolinska Institutet.; Karolinska Institutet.; [1998]

    Abstract : The structure of Escherichia coli glutaredoxin 3 (Grx3) was investigated using NMR spectroscopy in combination with isotope labeling. Nearly complete sequence specific assignment were obtained for the reduced Grx3 using a 15N enriched protein sample. READ MORE