Search for dissertations about: "9q32"

Found 3 swedish dissertations containing the word 9q32.

  2. 1. Identifying Risk Genes for Cervical Cancer : Using Affected Sib-Pairs and Case-Control Materials from Sweden

    Author : Malin Engelmark; Ulf Gyllensten; Dan Holmberg; Uppsala universitet; []
    Keywords : Medicine; Cervical cancer; HPV; Affected sib-pairs; HLA; Fas; Genomewide scan; 9q32; TSCOT; Medicin;

    Abstract : Cervical cancer is a multifactorial disease. Infection by oncogenic types of the human papillomavirus (HPV) is the major environmental risk factor and host genetic susceptibility also influences disease development. The aim of this thesis is to identify and analyse risk genes involved in the genetic predisposition to cervical carcinoma. READ MORE

  4. 2. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer

    Author : Markus Heidenblad; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FISH; Clinical genetics; PCR; cDNA microarray; array-based CGH; expression profiling; genomic profiling; Pancreatic cancer; gene amplification; Klinisk genetik;

    Abstract : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. READ MORE

  5. 3. Molecular progression and clonality or urinary bladder cancer

    Author : Jari Louhelainen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The general aim of this work was to investigate the clonality of multifocal bladder tumours, chromosomal deletions and model the initiation-progression of bladder tumours at a molecular level using microsatellite analysis. In a population-based study, we found correlation between stage and grade and the prevalence of loss of heterozygosity (LOH) at all observed chromosome 13 loci and stage and grade, respectively. READ MORE