Search for dissertations about: "A-site"

Showing result 1 - 5 of 190 swedish dissertations containing the word A-site.

  1. 1. Receptor-ligand interactions of the human 5-HT1B receptor : A site-directed mutagenesis study

    Author : Charlotta Grånäs; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; 5-hydroxytryptamine; serotonin; 5-HT1B receptor; site-directed mutagenesis; signal transduction; sumatriptan; G protein; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : The 5-hydroxytryptamine (5-HT, serotonin)1B receptor is one of thirteen G protein-coupled 5-HT receptors. 5-HT is known to influence temperature regulation, pain, cognition and sexual and feeding behaviours. READ MORE

  2. 2. Study on the Function of Translation Initiation Factor IF1

    Author : Victor Croitoru; Leif A. Isaksson; Kim Kusk Mortensen; Stockholms universitet; []
    Keywords : translation; initiation factor IF1; mutagenesis; A-site; RNA chaperone; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Initiation is the first step in protein biosynthesis representing a fundamental event in cell life which determines fidelity, efficiency and regulation of gene expression. In addition to the ribosome and mRNA, three protein factors IF1, IF2 and IF3 are involved in the initiation of translation in prokaryotes. READ MORE

  3. 3. More than Meets the Eye : Transmedial entertainment as a site of pleasure, resistance and exploitation

    Author : Karin Fast; André Jansson; Michael Karlsson; Jonathan Gray; Karlstads universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Transmedial; entertainment; world; brand; media convergence; producer; consumer; fandom; power; Media and Communication Studies; Medie- och kommunikationsvetenskap;

    Abstract : Today’s converging entertainment industry creates ‘transmedial’ brand worlds in which consumers are expected to become immersed. Integrated marketing campaigns connected to these worlds encourage various kinds of consumer productivity and invite consumers to partake in brand-building processes. READ MORE

  4. 4. Characterization of a site-specific gene-transfer mechanism in bacteria

    Author : Karin Hansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmaceutical Microbiology; farmaceutisk mikrobiologi;

    Abstract : Integrons capture and rearrange single genes borne on mobile units called cassettes using site-specific recombination. The integrons increase the variation of antibiotic resistance among bacterial plasmids and may also reorganize clustered genes in bacterial genomes. READ MORE

  5. 5. The ribosome, stringent factor and the bacterial stringent response

    Author : Rose-Marie Jenvert; Lovisa Holmberg Schiavone; Suparna Sanyal; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; stringent factor; stringent response; tRNA; ribosomal protein L11; pppGpp; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : The stringent response plays a significant role in the survival of bacteria during different environmental conditions. It is activated by the binding of stringent factor (SF) to stalled ribosomes that have an unacylated tRNA in the ribosomal A-site which leads to the synthesis of (p)ppGpp. READ MORE