Search for dissertations about: "A. Dax"

Showing result 1 - 5 of 7 swedish dissertations containing the words A. Dax.

  2. 1. Modulation of nuclear receptor activity by a unique class of corepressors

    Author : Elin Holter; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nuclear receptors; corepressors; transcription; intracellular localization.;

    Abstract : Nuclear receptors comprise a unique family of transcription factors that are crucial regulators of gene expression involved in diverse physiological and developmental processes. The nuclear receptor field has undergone a very rapid development during the recent two decades due to the recognition of the importance of nuclear receptors as intracellular signal transmitters and pharmaceutical targets. READ MORE

  4. 2. Estrogen receptor signalling in mammary epithelial cells

    Author : Malin Hedengran Faulds; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ER; STAT5; mammary epithelial cell differentiation; EGF; DAX-1;

    Abstract : The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and epidermal growth factor (EGF). READ MORE

  5. 3. Efficient carbohydrate synthesis by controlled inversion strategies

    Author : Hai Dong; Olof Ramström; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate Chemistry; Carbohydrate Protection; Epimerization; Inversion; Dynamic; Regioselective Control; Neighboring Group Participation; Organic chemistry; Organisk kemi;

    Abstract : The Lattrell-Dax method of nitrite-mediated substitution of carbohydrate triflates is an efficient method to generate structures of inverse configuration. In this study it has been demonstrated that a neighboring equatorial ester group plays a highly important role in this carbohydrate epimerization reaction, inducing the formation of inversion compounds in good yields. READ MORE

  6. 4. Efficient Carbohydrate Synthesis By Intra- and Supramolecular Control

    Author : Hai Dong; Olof Ramström; Ulf Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate Chemistry; Supramolecular Control; Ambident Reactivity; Bioorganic chemistry; Bioorganisk kemi;

    Abstract : The Lattrell-Dax method of nitrite-mediated substitution of carbohydrate triflates is an efficient method to generate structures of inverse configuration. In this study, the effects of the neighboring group on the Lattrell-Dax inversion were explored. READ MORE

  7. 5. Modulation of nuclear receptor signaling by RBR ubiquitin ligases

    Author : Nina Gustafsson Sheppard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nuclear receptors (NRs) constitute a superfamily of transcription factors and play important roles in physiology. Transcriptional regulation by NRs can be modulated through interactions with various coregulators that activate or repress transcription through mediating receptor and chromatin modifications as well as communicating with the general transcription factor machinery. READ MORE