Search for dissertations about: "A549"
Showing result 1 - 5 of 35 swedish dissertations containing the word A549.
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1. Metal Particles – Hazard or Risk? Elaboration and Implementation of a Research Strategy from a Surface and Corrosion Perspective
Abstract : Do metal particles (including particles of pure metals, alloys, metal oxides and compounds) pose a hazard or risk to human health? In the light of this question, this thesis summarizes results from research conducted on metal particles, and describes the elaboration and implementation of an in vitro test methodology to study metal release from particles through corrosion and dissolution processes in synthetic biological media relevant for human exposure through inhalation/ingestion and dermal contact. Bioaccessible metals are defined as the pool of released metals from particles that potentially could be made available for absorption by humans or other organisms. READ MORE
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2. Multidimensional Modulation Formats for Coherent Optical Communication Systems
Abstract : Coherent optical receivers have enabled the use of multilevel modulation formats with high spectral efficiencies and long transmission reaches. Traditionally, modulation formats utilizing the two dimensions spanned by the amplitude and the phase of the signal have been dominating. READ MORE
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3. Discordant Neural Xenografting: Analysis and Modulation of Immune Responses
Abstract : Transplantation of embryonic human neural tissue can restore function in patients with Parkinson’s disease, but there is a severe shortage of donor tissue which limits the applicability of the technique. Embryonic neural tissue from other species, xenogeneic tissue, would provide a readily accessible donor tissue with the potential to help patients if the immunological reactions in the host could be prevented. READ MORE
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4. Engineered nanomaterials in in vivo and in vitro models
Abstract : Nanotechnology and engineered nanomaterials (ENM) empower existing technologies. One of the great examples are III-V semiconductor nanowires (NW), which have a broad application range. The occupational safety and hazard organizations draw attention to ENM, as their physical and chemical characteristics differ from the ones of bulk materials. READ MORE
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5. Polycyclic aromatic hydrocarbons : DNA damage and cell signaling
Abstract : Oxidative stress is a threat to our wellbeing. The formation of reactive oxygen species may result in oxidative lesions in DNA and RNA. When challenging A549 cells with 18O-labeled hydrogen peroxide, we found that RNA was between 14-25 times more sensitive to [18O]-8-oxoGuo formation than [18O]-8-oxodGuo formation in DNA. READ MORE