Search for dissertations about: "ALS"
Showing result 6 - 10 of 162 swedish dissertations containing the word ALS.
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6. Zinc in folding and misfolding of SOD1 : Implications for ALS
Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and lower motor neurons. Most ALS cases are sporadic; only 6% are associated with mutations in Cu, Zn superoxide dismutase (SOD1). READ MORE
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7. Search for Biomarkers in ALS and Parkinson's Disease : Positron Emission Tomography and Cerebrospinal Fluid Studies
Abstract : New biomarkers are needed to improve knowledge about pathophysiology, in order to provide earlier correct diagnosis and to follow disease progression of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The aim of this thesis was to find new biomarkers for these diseases. READ MORE
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8. SOD1´s Law : An Investigation of ALS Provoking Properties in SOD1
Abstract : Proteins are the most important molecules in the cell since they take care of most of the biological functions which resemble life. To ensure that everything is working properly the cell has a rigorous control system to monitor the proper function of its proteins and sends old or dysfunctional proteins for degradation. READ MORE
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9. SOD, ORF and ALS: On the role of SOD1 and C9ORF72 in the pathogenesis of ALS
Abstract : Amyotrophic lateral sclerosis (ALS) is characterized by adult-onset degeneration of upper and lower motor neurons. Symptoms begin focally in one muscle and then spread contiguously, resulting in progressive paralysis and death from respiratory failure. READ MORE
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10. SOD1 prions transmit templated aggregation and fatal ALS-like disease
Abstract : Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disease characterized by a progressive degeneration of the upper and lower motor neurons. The resulting paresis begins focally, usually in one muscle, and spreads contiguously, leading to muscle wasting, progressive paralysis and eventually death. READ MORE