Search for dissertations about: "Abnormal development"

Showing result 1 - 5 of 221 swedish dissertations containing the words Abnormal development.

  2. 1. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

    Author : Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Abstract : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. READ MORE

  4. 2. The role of PDGF-A in lung development, injury and repair

    Author : Leonor Gouveia; Johanna Andrae; Christer Betsholtz; Brigid Hogan; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lung; organogenesis; PDGF; signalling pathway; development;

    Abstract : The developmental processes that take place during embryogenesis depend on a great number of proteins that are important for cell-to-cell communication. Platelet-derived growth factors are known to be important for epithelial-mesenchymal interactions during development and organogenesis. READ MORE

  5. 3. Markers and mechanisms of abnormal neurovascular development in the preterm infant

    Author : William Hellström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neonatology; Brain development; Extremely preterm infant; Brain volume; Retinopathy of prematurity; Insulin-like growth factor 1; Neurofilament light; Neurodevelopment;

    Abstract : Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes are sparse. READ MORE

  6. 4. Development in children born very preterm after intrauterine growth restriction with abnormal fetal blood flow

    Author : Eva Morsing; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; umbilical artery; cognitive development; lung function; cardiovascular function; very preterm infants; Doppler ultrasound; Intrauterine growth restriction;

    Abstract : Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. READ MORE

  7. 5. Influence of inflammation and of stage of lung development on the development of neonatal lung injury

    Author : Erica Bäckström; Göteborgs universitet; []
    Keywords : premature birth; BPD; inflammation; IL-1β; lung development; gastric aspirates;

    Abstract : Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological characteristics of BPD. Interleukin (IL)-1β is a central cytokine in inflammation. READ MORE