Search for dissertations about: "Adenosine Triphosphate metabolism"

Showing result 1 - 5 of 12 swedish dissertations containing the words Adenosine Triphosphate metabolism.

  2. 1. Cell signalling in cancer. A functional and immunochemical investigation of purinergic,adrenergic, nitrergic, and prostaglandin mediated signalling mechanisms in experimental and human cancer

    Author : Gunnar Nylund; Göteborgs universitet; []
    Keywords : adenosine-5´-triphosphate; colon cancer; extracellular acidification; melanoma; ; microphysiometer; nitric oxide; noradrenaline; prostaglandin E2; sarcoma; tumour cell; metabolism; uridine-5´-triphosphate;

    Abstract : Disturbed cell signalling is a hallmark of the cancer cell, being one important mechanismbehind uncontrolled cell growth. In the current study, we have investigated cancer cellsignalling with the focus on some first messenger and/or their receptors, in the murine celllines, MCG 101, and K1735-M2, and the human colon cancer cell line, HT-29. READ MORE

  4. 2. Myocardial metabolism in experimental infarction and heart failure

    Author : Truls Råmunddal; Göteborgs universitet; []
    Keywords : Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Abstract : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. READ MORE

  5. 3. Myocardial creatine metabolism in experimental infarction and heart failure

    Author : Malin Lindbom; Göteborgs universitet; []
    Keywords : Energy metabolism; Creatine; Congestive heart failure; Myocardial infarction; Ventricular arrhythmias; Cardiac remodeling; apolipoprotein B; Lipid metabolism;

    Abstract : The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as pathologic remodelling. An important part of this negative remodelling process is disturbances in the myocardial energy metabolism. READ MORE

  6. 4. Energy Metabolic Stress Syndrome : Impact of Physical Activity of Different Intensity and Duration

    Author : Stefan Branth; Leif Hambraeus; Gunnar Ronquist; Mats Stridsberg; Lennart Kaijser; Uppsala universitet; []
    Keywords : Medicine; energy; ATP; metabolism; nutrition; body-composition; physical-activity; stress; insulin-resistance; ion-pumps; intracellular swelling and -shrinkage; taurine; reactive oxygen species; Medicin;

    Abstract : All living cell functions require an ongoing supply of energy derived from carbohydrates, lipids and proteins with their own pathways of breakdown. All of them end up in the oxidation of reduced coenzymes, yielding chemically-bound energy in the form of adenosine triphosphate (ATP). READ MORE

  7. 5. Adipose and muscle tissue metabolism in cancer cachexia

    Author : Thorhallur Agustsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Loss of adipose and muscle tissue mass is a key feature of cancer cachexia. Weight loss, glucose intolerance, and insulin resistance are seen in patients with pancreatic ductal adenocarcinoma (PDAC). READ MORE