Search for dissertations about: "Adverse drug reactions"

Showing result 1 - 5 of 76 swedish dissertations containing the words Adverse drug reactions.

  2. 1. Hazards of Drug Therapy : On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

    Author : Karin Hedenmalm; Marja-Liisa Dahl; Gunnar Alvan; Ellen Vinge; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. READ MORE

  4. 2. Spontaneous reporting of adverse drug reactions : Possibilities and limitations

    Author : Martin Bäckström; Tom Mjörndal; Rune Dahlqvist; Folke Sjökvist; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting; metamizole; general practitioners; hospital physicians; under-reporting; economical inducement; nurses.; Farmakologi; Pharmacological research; Farmakologisk forskning; Clinical Pharmacology; klinisk farmakologi;

    Abstract : Adverse drug reactions (ADRs) constitute a major problem in society and in drug therapy. They are a common cause of short-term hospitalization, prolonged hospitalization and death. Spontaneous reporting of ADRs remains one the most effective methods for detecting new and serious drug reactions. READ MORE

  5. 3. Drug interaction surveillance using individual case safety reports

    Author : Johanna Strandell; Staffan Hägg; Niklas Norén; Andrew Bate; Robin E. Ferner; Linköpings universitet; []
    Keywords : Adverse drug reactions; adverse drug interaction surveillance; drug interactions; individual case safety reports; postmarketing pharmacovigilance; signal detection; MEDICINE; MEDICIN;

    Abstract : Background: Drug interactions resulting in adverse drug reactions (ADRs) represent a major health problem both for individuals and society in general. Post-marketing pharmacovigilance reporting databases with compiled individual case safety reports (ICSRs) have been shown to be particularly useful in the detection of novel drug - ADR combinations, though these reports have not been fully used to detect adverse drug interactions. READ MORE

  6. 4. Prostate Cancer; Metabolic Risk Factors, Drug Utilisation, Adverse Drug Reactions

    Author : Birgitta Grundmark; Lars Holmberg; Björn Zethelius; Gunnar Engström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Epidemiology; Pharmacoepidemiology; Metabolic Syndrome; Selenium; Smoking; hOGG1; MnSOD; Competing Risk; Adherence; Persistance; Medical Possession Ratio; MPR; Signal Detection; PRR; proportional reporting ratio; ULSAM; PcBaSE; EudraVigilance; SPDR; Swedish Prescribe Drug Registry; NPCR; National Prostate Cancer Registry; SDR; Signal; disproportionality analysis; PRR-TA; EudraVigilance; Epidemiology; Epidemiologi; Kirurgi; särskilt urologi; Urology; Oncology; Onkologi; Geriatrics; Geriatrik;

    Abstract : Increased possibilities during the last decades for early detection of prostate cancer have sparked research on preventable or treatable risk factors and on improvements in therapy. Treatments of the disease still entail significant side effects potentially affecting men during the rest of their lives. READ MORE

  7. 5. Potentially inappropriate drug treatment among older people with cognitive impairment

    Author : Eva Sönnerstam; Maria Gustafsson; Maria Sjölander; Hugo Lövheim; Ylva Böttiger; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Older people; major neurocognitive disorder; cognitive impairment; potentially inappropriate medications; drug-drug interactions; renal function; adverse drug reactions; nursing homes; time trends; Clinical Pharmacology; klinisk farmakologi;

    Abstract : Background: The aging process contributes to alterations in organ systems, which lead to an increased risk for chronic conditions. Drug treatment is an important strategy in the management of chronic conditions; however, pharmacokinetic and pharmacodynamic alterations contribute to increased sensitivity to drug effects. READ MORE