Search for dissertations about: "Alginate 3D culture"

Found 4 swedish dissertations containing the words Alginate 3D culture.

  1. 1. Modular Enzyme-Responsive Polysaccharide-Based Hydrogels for Biofabrication

    Author : Sajjad Naeimipour; Daniel Aili; Robert Selegård; Alireza Dolatshahi-Pirouz; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 3D cell-culture; Bioprinting; Alginate; Hyaluronan; Cancer model;

    Abstract : Engineered human tissue and disease models can decrease the cost and time of developing new drugs and treatments, facilitate personalized medicine, and eliminate the need for animal models that poorly represent the human body and are ethically problematic. However, the current conventional cell expansion methods using 2D culture flasks cannot enable the development of such complex multi-cellular 3D models. READ MORE

  2. 2. Active cellular forces in variable mechanical microenvironments

    Author : Adele Khavari; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traction force; Gradient substrate; Alginate 3D culture; Durotaxis; mechanics;

    Abstract : Our bodies are immensely complex structures, with various systems, organs, and processes that are not only biochemically driven, but strongly dependent on physical mechanics.  At the heart of all these processes are cells, which must generate forces to adhere, spread, differentiate, grow, and move. READ MORE

  3. 3. Biofabrication, Biomechanics and Biocompatibility of Nanocellulose-based Scaffolds for Auricular Cartilage Regeneration

    Author : Hector Martinez Avila; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nasoseptal Chondrocytes; Tissue Engineering; Auricular Cartilage; Auricular reconstruction; Bacterial Nanocellulose; Neocartilage; Nanofibrillated Cellulose; Mononuclear Cells; 3D Bioprinting;

    Abstract : In about 2:10,000 births the external part of the ear, the auricle, is severely malformed or absent. Furthermore, tumors and trauma can cause defects to the auricle. READ MORE

  4. 4. Generation and investigation of neural microenvironment in health and disease

    Author : Jakub Lewicki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells in our body are under the constant influence of intrinsic and extrinsic factors that modulate their behavior. Early on, starting during the development of the organism, growth factors, nutrients, oxygen, the extracellular matrix and contact with other cells affect essential processes such as proliferation, migration, differentiation and apoptosis. READ MORE