Search for dissertations about: "Aman Russom"

Showing result 1 - 5 of 17 swedish dissertations containing the words Aman Russom.

  2. 1. Microfluidic bead-based methods for DNA analysis

    Author : Aman Russom; Ulf Gyllensten; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; single nucleotide polymorphism; DNA analysis; SNP; microfluidics; pyrosequencing; beads; lab on a chip; hybridization; DASH; microsystem; micro totat analysis system; allele-specific extension; DASH; microcontact printing; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. READ MORE

  4. 2. Utilizing Biopolymers in 3D Tumor Modeling and Tumor Diagnosis

    Author : Negar Abbasi Aval; Torbjörn Pettersson; Aman Russom; Maria Tenje; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D tumor modeling; Spheroids; Cellulose Nano Fibrils; Layer by Layer; Extracellular matrix; Circulating Tumor Capturing; Pancreatic ductal adenocarcinoma PDAC ; 3D-tumörmodellering; Sfärer; Cellulosa; Lager-på-lager; Extracellulärmatris; Infångning av cirkulerande tumörceller; Mänskliga Duktala Adenocarcinom-Hepatocyter; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Cancer represents a significant global public health challenge and ranks as the second mostcommon cause of death in the United States. The onset of cancer entails an initial phasewhere cells lose their polarity and disconnect from the normal basement membrane, allowingthem to form distinct three-dimensional (3D) configurations that interact with adjacent cellsand the surrounding microenvironment. READ MORE

  5. 3. Centrifugal microfluidics-based point of care diagnostics at resource limited settings

    Author : Ahmad Saleem Akhtar; Aman Russom; Ines Fernandes Pinto; Nicole Pamme; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microfluidics; centrifugal microfluidics; point-of-care; low-cost; diagnostics; agarose beads; immunoassays; colorimetry; fluorescence; cytokines; nucleic acid amplification; isothermal amplification; COVID-19; portable; smartphone; resource limited settings.; Biotechnology; Bioteknologi;

    Abstract : Advancements in medical diagnostics have allowed us to understand the underlying mechanism and treat the root cause for many diseases which had been causing morbidity and mortality up until this point in human history. Furthermore, many of the standard diagnostic procedures have now been transformed to provide answers at or near the point-of-care. READ MORE

  6. 4. Microfluidic bases sample preparation for blood stream infections

    Author : Sahar Ardabili; Aman Russom; Mats Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sample-preparation; microfluidics; sepsis; size-based separation; selective cell-lysis; immune-based isolation; Biotechnology; Bioteknologi;

    Abstract : Microfluidics promises to re-shape the current health-care system by transferring diagnostic tools from central laboratories to close vicinity of the patient (point-of-care). One of the most important operational steps in any diagnostic platform is sample preparation, which is the main subject in this thesis. READ MORE

  7. 5. Point of care microfluidic tool development for resource limited settings

    Author : Indradumna Banerjee; Aman Russom; Luca Brandt; Gustaf Mårtensson; Jens Ducrée; KTH; []
    Keywords : Blood; control; cell separation; centrifugal microfluidics; diagnostics; elasto-inertial; hematocrit level; microfluidics; neonatal diagnostics; nucleic acid quantification; point of care; particle focusing; resource limited settings.; Bioteknologi; Biotechnology;

    Abstract : The development of point of care diagnostics using recent advances in microfluidics have the potential to transform health care in several ways, especially in resource limited settings with limited access to advanced health care infrastructure. However, translating a point of care device to reality is often a challenging task because of the complexities involved in integrating a number of diverse engineering concepts into an easy to use, accurate and portable device. READ MORE