Search for dissertations about: "Anna K Överby"

Found 4 swedish dissertations containing the words Anna K Överby.

  1. 1. Uukuniemi virus-like particles : a model system for bunyaviral assembly

    Author : Anna K Överby; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Viruses are intracellular parasites that are unable to multiply except when inside a living cell of a host. Outside their host they remain inert. READ MORE

  2. 2. Identification and evaluation of antiviral compounds targeting Rift Valley fever virus

    Author : Koushikul Islam; Clas Ahlm; Magnus Evander; Anna K. Överby; Johan Neyts; Umeå universitet; []
    Keywords : Rift Valley fever virus; antiviral; assay development; screening; drug discovery;

    Abstract : Rift Valley fever virus (RVFV), a negative-stranded RNA virus, is the etiological agent of the vector-borne zoonotic disease Rift Valley fever (RVF). RVFV causes significant morbidity and mortality in humans and livestock throughout Africa and the Arabian Peninsula. READ MORE

  3. 3. Host-pathogen interactions during tick-borne flavivirus infection : pathogenesis, tropism and tools

    Author : Ebba Rosendal; Anna K. Överby Wernstedt; Emma Nilsson; Jonathan D. Gilthorpe; Sonja M. Best; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tick-borne encephalitis virus; Langat virus; pathogenesis; type I interferons; central nervous system; neuroinflammation; structural proteins; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

    Abstract : Tick-borne encephalitis virus (TBEV) is a neurotropic member of the genus Flavivirus. It may transmit to humans through the bite of an infected tick or consumption of unpasteurized dairyproducts, and causes tick-borne encephalitis (TBE). TBE constitutes a significant health burden in Eurasia, with more than 10,000 cases reported every year. READ MORE

  4. 4. Viperin, a multifunctional radical SAM enzyme : biogenesis and antiviral mechanisms

    Author : Arunkumar Upadhyay; Anna K. Överby; Niklas Arnberg; Richard Lundmark; Michael Beard; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Viperin (virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is an interferon-induced antiviral protein. It has three distinct functional domains: the N-terminal domain, the radical SAM (S-adenosylmethionine) domain for binding iron-sulphur cluster, and the C-terminus domain. READ MORE