Search for dissertations about: "Apoptosis Regulatory Proteins"

Showing result 1 - 5 of 57 swedish dissertations containing the words Apoptosis Regulatory Proteins.

  2. 1. Structural studies of proteins in apoptosis and lipid signaling

    Author : Maria Dolores Herman Moreno; Pär Nordlund; Markus Gruetter; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteins; crystal structure; apoptosis; cancer; CoFi-Blot; kinases; lipid signaling; Structural biology; Strukturbiologi; Structural Biology; strukturbiologi;

    Abstract : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. READ MORE

  4. 2. Novel Interactors of X-linked Inhibitor of Apoptosis Protein : Expression and Effects on Tumor Cell Death

    Author : Håkan Steen; Dan Lindholm; Bertrand Joseph; Uppsala universitet; []
    Keywords : Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

    Abstract : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. READ MORE

  5. 3. UVA/B induced redox alterations and apoptosis in human melanocytes

    Author : Petra Wäster Larsson; Inger Rosdahl; Karin Öllinger; Ian Cotgreave; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; UV; melanocyte; apoptosis; glutathione; p53; Dermatology and venerology; Dermatologi och venerologi;

    Abstract : Malignant melanoma is one of the most rapidly increasing cancers and accounts for about three-quarter of all skin cancer deaths worldwide. Despite compelling evidence that ultraviolet (UV) irradiation causes melanoma the knowledge how various wavelength spectra affect the balance between proliferation and apoptosis controlling the homeostasis of the melanocyte population is still limited. READ MORE

  6. 4. Regulation of Polyamine Analogue-Induced Apoptosis in Human Breast Cancer Cells

    Author : Martina Holst; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cancer; Animal physiology; Djurfysiologi; Pharmacological sciences; pharmacognosy; pharmacy; onkologi; Cytologi; cancerology; oncology; Cytochrome c; Cytology; Bcl-2; Mitochondrial respiration; Apoptosis; Human breast cancer cells; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Social medicine; Socialmedicin; samhällsmedicin; Mitochondria; Polyamine analogues;

    Abstract : Apoptosis is a defined process for cells to commit suicide through a set of biochemical and morphological cell changes. Activated apoptotic signals converge on the mitochondria, leading to permeabilization of mitochondrial membranes and release of different apoptosis regulatory proteins into the cytosol. READ MORE

  7. 5. Immunomodulation during human pregnancy : placental exosomes as vehicles of immune suppression

    Author : Ann-Christin Stenqvist; Lucia Mincheva-Nilsson; Maria Jenmalm; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; exosomes; microvesicles; pregnancy; placenta; syncytiotrophoblast; immune privilege; apoptosis; cytotoxicity; T regulatory cells; NKG2D; MICA B; FasL; TRAIL; immunologi; Immunology;

    Abstract : The mammalian pregnancy comprises a challenge to the maternal immune system since the fetus is semi-allogeneic and could thus be rejected. Pregnancy success is associated with the placenta that is not only essential for oxygen supply, nourishment and pregnancy hormones but also plays a role in the protection of the fetus against maternal immunologic attack. READ MORE