Search for dissertations about: "Astrocytes"

Showing result 1 - 5 of 242 swedish dissertations containing the word Astrocytes.

  2. 1. Astrocytes, reactive gliosis and CNS regeneration

    Author : Ulrika Wilhelmsson; Göteborgs universitet; []
    Keywords : CNS regeneration; astrocytes; reactive gliosis; intermediate filaments;

    Abstract : The regenerative capacity in the adult central nervous system (CNS) is very limited, and the glial cells have been implicated in the inhibition of CNS regeneration. In essentially all CNS pathologies, astrocytes are activated and this process is known as reactive gliosis. READ MORE

  4. 2. Interaction between nerve fiber formation and astrocytes

    Author : Sanazalsadat Hashemian; Ingrid Strömberg; Elisabet Åkesson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; spinal cord; CSPG; CD47;

    Abstract : Parkinson’s disease, the second most common neurodegenerative disorder,is characterized by loss of nigrostriatal dopaminergic neurons. To date,there is no defined cause and cure for the disease. An ideal treatmentstrategy is to replace the lost neurons by transplanting fetal dopaminergicneurons to the brain of parkinsonian patients. READ MORE

  5. 3. Cellular responses to amyloid-beta protofibrils : Focus on astrocytes, extracellular vesicles and antibody treatment

    Author : Elisabeth Nikitidou; Anna Erlandsson; Martin Ingelsson; Gunnar K. Gouras; Uppsala universitet; []
    Keywords : Alzheimer’s disease; Amyloid-beta; Protofibrils; Astrocytes; Extracellular vesicles; Antibody; Neurons; Degradation; Medicinsk vetenskap; Medical Science;

    Abstract : Knowledge about the cellular mechanisms behind the initiation and propagation of Alzheimer’s disease (AD) is limited. Decades of research have focused on neuronal abnormalities in AD, but recently more attention has been given to the glial cells. READ MORE

  6. 4. The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma

    Author : Lizhen Li; Göteborgs universitet; []
    Keywords : astrocytes; intermediate filaments; GFAP; vimentin; reactive gliosis; brain ischemia; neurotrauma;

    Abstract : Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and maintenance of the blood brain barrier, as well as the induction and stabilization of neuronal synapses. READ MORE

  7. 5. Generation of human astrocytes for disease modeling. A study based on stem cells, direct conversion and genome engineering to dissect the role of astrocytes in leukodystrophies

    Author : Ella Quist; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Stem Cells; transcription factor programming; direct conversion; genome engineering; CRISPR Cas9; leukodystrophy;

    Abstract : Astrocytes are one of the major cell types in the central nervous system and are indispensable for brain development and function. The human brain and human astrocytes have unique structures and functions that are not present in other animal species. READ MORE