Search for dissertations about: "Asymmetric Horner-Wadsworth-Emmons"

Found 4 swedish dissertations containing the words Asymmetric Horner-Wadsworth-Emmons.

  2. 1. Methods for Asymmetric Olefination Reactions; Development and Application to Natural Product Synthesis

    Author : Daniel Strand; Tobias Rein; Viresh Rawal; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antitumor agents; Asymmetric Horner-Wadsworth-Emmons; Desymmetrization; Metal-catalyzed olefination; Mucocin; Palladium-catalyzed allylic substitution; Parallel kinetic resolution; Pyranicin; Pyragonicin; Rhenium; Stereoconvergent synthesis; Stereodivergent synthesis; Stereoselective synthesis; Tetrahydropyran; Wittig reaction; Organic chemistry; Organisk kemi;

    Abstract : This thesis deals with the development and application of methods for asymmetric olefinations, in particular Horner-Wadsworth-Emmons (HWE) reactions, in the synthesis of certain natural products. Relying on asymmetric HWE reactions to access key building blocks, two natu-ral products, pyranicin and pyragonicin, were synthesized from common late intermediates. READ MORE

  4. 2. Synthetic approaches to chiral tetrahydropyran and tetrahydrofuran derivatives by use of asymmetric Horner-Wadsworth-Emmons reactions

    Author : Lauri Vares; KTH; []
    Keywords : ;

    Abstract : .... READ MORE

  5. 3. Synthesis of aromatic bis- and tris(amino acids) and chiral dendrimers

    Author : Andreas Ritzén; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; HWE reaction; asymmetric hydrogenation; Heck reaction; Amino acids; chiral dendrimers;

    Abstract : A number of protected aromatic bis- and tris(amino acids) have been synthesised by catalytic asymmetric hydrogenation of the corresponding didehydroamino acid derivatives. The didehydroamino acid derivatives were prepared either by a Heck coupling of a 2-amidoacrylate with an aryl dihalide, or by Horner-Wadsworth-Emmons olefination of aromatic aldehydes with phosphonylglycine reagents. READ MORE

  6. 4. Non Natural Aromatic Amino Acids Applications in cage-construction, metal ion coordination and asymmetric catalysis

    Author : Ruxandra Ionescu; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; diethylzinc additions.; spectroscopy; metal ion coordination; cage-like compounds; Amino acids; C3-symmetry; Organic chemistry; Organisk kemi;

    Abstract : Aromatic non-natural amino acids, the outstanding feature of which was the presence of several arms, were synthesised and their properties investigated. The amino acids were synthesised following a standard procedure starting with a Horner-Wadsworth-Emmons or a Heck reaction, which provided didehydroamino acids. READ MORE