Search for dissertations about: "Athymic mice"

Showing result 1 - 5 of 22 swedish dissertations containing the words Athymic mice.

  2. 1. Development and validation of a localized murine candidiasis model : The pathogenesis, chemotheraphy and defense mechanisms to Candida mastitis in the lactating mouse

    Author : Faisal Abdi Guhad; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Murine model; Candida albicans; Pathogenesis; Virulence factors; Amphotericin B; Fluconazole; Complement activation; C3c; SCID mice; Nude mice; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : A murine model of localized candidiasis (mastitis) was developed. The model was analyzed withrespect to its discriminative abilities through investigation of the virulence properties of C.albicans mutant strains compared with the wild-type parental strain. READ MORE

  4. 2. Phytoestrogens and prostate cancer : experimental, clinical, and epidemiological studies

    Author : Annika Bylund; Pär Stattiin; Anders Bergh; Göran Hallmans; Swen-Olof Andersson; Umeå universitet; []
    Keywords : prostatic neoplasm; phytoestrogens; lignans; enterolactone; rye; 7-hydroxymataireorcinol; nude mice; TRAMP mice; nested case control study; LNCaP; Oncology; onkologi;

    Abstract : Dietary factors may affect development and progression of prostate cancer. Experimental and epidemiological studies have suggested an effect of phytoestrogens on prostate cancer. Lignans are the predominant phytoestrogen in a Western diet. READ MORE

  5. 3. Development of the gastrointestinal tract in young mammals : Effects of enteral provocation with protease or phytohaemagglutinin in neonatal rats

    Author : Ester Arevalo Sureda; Funktionell zoologi; []
    Keywords : gut; Intestine; Pancreas; development; precocious; protease; PHA; enterocytes; permeability; endocytosis; IgG; FcRn; Blimp1; T-lymphocyte; passive immunity; altricial; neonatal; suckling; athymic; rat; immunohistochemistry IHC ;

    Abstract : The rat, as an altritial species, is born with an immature gastrointestinal tract and intestinal barrier function, which is highly absorptive to milk-borne bioactive molecules that can pass undigested and reach the general circulation of the suckling newborn. This passage occurs by the neonatal-Fc-receptor (FcRn) binding and trancytosis of immunoglobulin G in the proximal small intestine (SI) and by the highly endocytic vacuolated enterocytes non-selectively in the distal SI. READ MORE

  6. 4. Preservation of parathyroid function in thyroid and parathyroid surgery

    Author : Stefan Ander; Göran Åkerström; Linköpings universitet; []
    Keywords : Human parathyroid glands; vascular supply; parathyroid preservation; laser Doppler flowmetry; iPTH; autotransplantation; xenotransplantation; a thymic mice; angiogenesis; immunohistochemistry; electron microscopy; ultrastructure; autoradiography; MEDICINE; MEDICIN;

    Abstract : Preservation of normal parathyroid function and calcium homeostasis after operations on the thyroid and parathyroid glands is a difficult assignment in endocrine surgery, and it is crucial to minimise the risks of permanent postoperative hypoparathyroidism. The aim of this thesis was to study the vascular supply of the parathyroid glands and the revascularisation, growth, and function of transplanted parathyroid tissue, in order to add new information about parathyroid preservation. READ MORE

  7. 5. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Author : Sukanya Raghavan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Abstract : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. READ MORE