Search for dissertations about: "Aurélie Ambrosi"

Found 1 swedish dissertation containing the words Aurélie Ambrosi.

2. 1. The TRIM21/Ro52 E3 ligase and its antibodies in autoimmune disease

   Author : Aurélie Ambrosi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Patients with the systemic autoimmune diseases systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS) often have autoantibodies against Ro/SSA (composed of the TRIM21/Ro52 and Ro60 antigens) and La/SSB. The biological function of the TRIM21/Ro52 protein itself has remained unknown until its recent description as a tripartite-motif (TRIM) family member and an E3 ligase involved in ubiquitination. READ MORE