Search for dissertations about: "Aurelija Jucaite"

Found 1 swedish dissertation containing the words Aurelija Jucaite.

2. 1. Attention-deficit/hyperactivity disorder : alterations of motor behaviour and dopaminergic transmission

   Author : Aurelija Jucaite; Karolinska Institutet; Karolinska Institutet; []
   Keywords : AD HD; DCD; neurodevelopmental disorder; PET; dopamine transporter; dopamine D2 receptors; raclopride; striatum; midbrain; anticipatory postural adjustments;

   Abstract : Altered catecholaminergic neurotransmission in the brain has long been thought to be of importance in the regulation of motor behavior and cognitive performance in children who had symptoms of distractability, impulsivity and clumsiness. The dopamine theory of AD/HD has mainly been substantiated by: i) the effects of psychostimulants, which target the dopamine transporter (DAT), and thereby reduce impulsiveness and inattentiveness, increase the striatal cerebral blood flow and functional activity, and ii) the evidence from linkage studies associating the AD/HD syndrome with allelic variations of genes encoding the dopamine transporter and, possibly, the dopamine D4 receptors. READ MORE