Search for dissertations about: "Autoantibodies : immunology"
Showing result 1 - 5 of 44 swedish dissertations containing the words Autoantibodies : immunology.
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1. Defining the genetics of systemic autoimmunity in mouse models of lupus
Abstract : Systemic Lupus Erythematosus (SLE) is a chronic multi-organ autoimmune disease considered a prototype for autoantibody and immune complex-mediated tissue injury. Although autoantibodies against a wide diversity of self-antigens are characteristically found in this disease, an important hallmark is the presence of autoantibodies to nuclear antigens. READ MORE
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2. Studies of immunological risk factors in type 1 diabetes
Abstract : Background: Type 1 diabetes (T1D) is a chronic, autoimmune disease caused by a T cell mediated destruction of ß-cells in pancreas. The development of T1D is determined by a combination of genetic susceptibility genes and environmental factors involved in the pathogenesis of T1D. READ MORE
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3. Metab-Immune analysis of the non-obese diabetic mouse
Abstract : Type 1A diabetes mellitus or T1D is a chronic disease characterized by T cell mediated destruction of the insulin producing β cells in the islets of Langerhans. The classical symptoms include high glucose levels in urine and blood, polyuria, and polydipsia. READ MORE
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4. The PD-1 pathway and the complement system in systemic lupus erythematosus
Abstract : Autoimmune diseases occur in up to 3-5% of the general population and represent a diverse collection of diseases with regards to clinical manifestations. The unifying factor of autoimmune diseases is tissue and organ damage as a result of an immune response mounted against self-antigens. READ MORE
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5. Identification of candidate genes involved in Mercury Toxicokinetics and Mercury Induced Autoimmunity
Abstract : BACKGROUND: Autoimmune diseases require the involvement and activation of immune cells and occur when the body builds up an immune response against its own tissues. This process takes place due to the inability to distinguish self-antigen from foreign antigen. Systemic autoimmunity represents an important cause of morbidity and mortality in humans. READ MORE