Search for dissertations about: "Autoradiography"

Showing result 1 - 5 of 95 swedish dissertations containing the word Autoradiography.

  1. 1. Preclinical Molecular Imaging using Multi-Isotope Digital Autoradiography - Techniques and Applications

    Author : Anders Örbom; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoradiography; Radioimmunotherapy; Antibodies; Molecular Imaging; Multi-Radionuclide Imaging; Silicon-strip detector;

    Abstract : Molecular imaging, both in vivo and ex vivo, is playing an increasingly important role in preclinical medical research. When using radionuclide-labeled tracers, e.g. in the development of radiopharmaceuticals for diagnostic imaging or for radionuclide therapy, quantitative in vivo imaging can be performed using emission tomography. READ MORE

  2. 2. Small-Scale Dosimetry for the Testis: Applications in Nuclear Medicine Diagnostics and Therapy

    Author : Suaad Meerkhan; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Testis; 111-In; Autoradiography; Biodistribution; Small-Scale; Monte Carlo; Dosimetry; spermatogonia; gammaH2AX; immunofluorescence;

    Abstract : It is well known that the testicles are among the most radiosensitive tissue, and constitute an important critical target for both external and internal radiation during diagnostic and therapeutic use of radionuclides. In systemic radionuclide therapy where very high activities are administered, the testis may become a dose-limiting organ; often with a complex, non-uniform activity distribution and a resulting non-uniform absorbed-dose distribution. READ MORE

  3. 3. Beta Camera: Development and applications

    Author : Kaj Ljunggren; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; medical instrumentation; tomography; radiology; Clinical physics; microchannel plate; radionuclides; scintillator; autoradiography; Beta Camera;

    Abstract : A new detector for on-line digital detection of charged particles (beta-particles, conversion electrons and alpha-particles) from thin samples for rapid autoradiography has been developed; the Beta Camera. The device consists of a photon-sensitive detector (image photon detector, IPD); the main component of which is a microchannel plate. READ MORE

  4. 4. Abdominal Aortic Aneurysm : Molecular Imaging Studies of Pathophysiology

    Author : Gustaf Tegler; Anders Wanhainen; Martin Björck; Jens Sörensen; Lars Norgren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysm; AAA; Positron emission tomography; PET; Molecular Imaging; Pathophysiology; Autoradiography; Angiogenesis; integrin alphaVbeta3; FDG; 18F-FDG; 11C-PK11195; 11C-D-deprenyl; [18F]fluciclatide; Fluciclatide; Bukaortaaneurysm; Molekylär bilddiagnostik; Patofysiologi; PET; Autoradiografi; Angiogenes; Surgery; Kirurgi; Medicinsk radiofysik; Medical Radiophysics;

    Abstract : The pathological process behind abdominal aortic aneurysm (AAA) formation is poorly understood and difficult to study. The aim of the thesis was to study the pathophysiology of AAA formation with positron emission tomography (PET) technology, a molecular imaging technique, allowing in vivo studies of pathophysiological changes. READ MORE

  5. 5. Olfactory Transfer of Analgesic Drugs After Nasal Administration

    Author : Ulrika Espefält Westin; Erik Björk; Eva Brittebo; Margareta Hammarlund-Udenaes; Paolo Colombo; Uppsala universitet; []
    Keywords : Pharmaceutics; Nasal administration; Olfactory transfer; Olfactory pathways; Central nervous system; Blood-brain barrier; Nasal respiratory mucosa; Olfactory mucosa; Olfactory bulb; Horizontal Ussing chamber; Morphine; Dihydroergotamine; Rat; Mouse; Swine; Autoradiography; Viability; Powder formulations; Galenisk farmaci;

    Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE