Search for dissertations about: "B Holm"

Showing result 1 - 5 of 10 swedish dissertations containing the words B Holm.

  2. 1. Platelets and airway remodeling : Mechanisms involved in platelet-induced fibroblast and airway smooth muscle cell proliferation in vitro

    Author : Ann-Charlotte B. Svensson Holm; Torbjörn Bengtsson; Eva Lindström; Mikael Adner; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Airway remodeling is a contributing cause to the pathological structural changes, such as increased cell proliferation, observed in asthma. Platelets have been found in autopsy lungmaterial obtained from asthmatic patients and are well known to induce proliferation in vitro of a variety of cells. READ MORE

  4. 2. Genetic and Epigenetic Characterisation of Breast Tumours

    Author : Karolina Holm; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; PIK3CA; PTEN; PI3K pathway; CCND1; microarrays; molecular subtypes; DNA methylation; EZH2; H3K27me3; PRC2; histone modification;

    Abstract : Breast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. READ MORE

  5. 3. Aggressive breast cancer : epidemiological studies addressing disease heterogeneity

    Author : Johanna Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer is either the number one or the second most common cause of cancer death in women in the world, depending on region¹. It is a cancer heterogeneous in many aspects related to the aggressiveness, such as proliferation rate, metastatic capacity and survival. READ MORE

  6. 4. Studies on Natural Variation and Evolution of Photoperiodism in Plants

    Author : Karl Holm; Ulf Lagercrantz; Martin Lascoux; Seth Jon Davis; Uppsala universitet; []
    Keywords : photoperiodism; circadian; flowering time; natural variation; evolution; Caspella bursa-pastoris; Physcomitrella patens; Biologi med inriktning mot evolutionär funktionsgenomik; Biology with specialization in Evolutionary Functional Genomics;

    Abstract : Photoperiodism refers to the organism’s ability to detect and respond to seasonal changes in the daily duration of light and dark and thus constitutes one of the most significant and complex examples of the interaction between the organism and its environment. This thesis attempts to describe the prevalence of variation in a photoperiodic response, its adaptive value, and its putative genetic basis in a common cruciferous weed, Capsella bursa-pastoris (Brassicaceae). READ MORE

  7. 5. Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes

    Author : Pernilla Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes mellitus is a common multifactorial disease that needs lifelong treatment of insulin and/or oral treatment to prevent hyperglycaemia. Despite treatment, patients with diabetes, still suffer from severe complications later in life. READ MORE