Search for dissertations about: "B cell development"

Showing result 1 - 5 of 707 swedish dissertations containing the words B cell development.

2. 1. Bone Development and the Nervous System

   Author : Gregor Sisask; Olof Nilsson; Anders Bjurholm; Kenneth B Jonsson; André Stark; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi;

   Abstract : Innervation of bone influence bone modeling, growth and remodeling. Pro-inflammatory cytokines released after tissue trauma are recognized as neurotrophic factors as well as factors influencing bone formation. The Wnt signaling pathway, essential for cell migration during embryogenesis is found to influence bone formation during fracture healing. READ MORE

4. 2. Functional collaboration between HLH transcription factors in B cell development

   Author : Ramiro Gisler; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

   Abstract : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. READ MORE

5. 3. B cell repertoire development in normal physiology and autoimmune disease

   Author : Åsa Andersson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cell repertoire; connectivity; natural antibodies; non-obese diabetic NOD ; Ig therapy; Vh7183 gene family;

   Abstract : The B cell repertoire in the neonatal immune system (IS) is characterised by reactivity towards self-components, including other immunoglobulin (Ig) V-regions. These properties have been suggested to be a requirement for the development of a normal immune system. READ MORE

6. 4. On the origin of B cells. Elucidating the Role of Tyrosine Kinase Receptors in B Cell Development

   Author : Alya Zriwil; Avdelningen för molekylär hematologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; B cell development; cytokine; tyrosine kinase receptors;

   Abstract : B cells are essential cells that are part of the adaptive immune system with the capacity to produce antibodies against exogenous antigens. These cells are produced through a process called hematopoiesis, tightly regulated by extrinsic and intrinsic factors. READ MORE

7. 5. Defining the role of CD47 and SIRPα in murine B cell homeostasis

   Author : Shrikant S Kolan; Per-Arne Oldenborg; Mikael Karlsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; CD47; SIRPα; Follicular B cell; Marginal zone macrophages; immunologi; Immunology;

   Abstract : B cell development is a highly organized process, which commences in the fetal liver during embryogenesis and in the bone marrow (BM) after birth. Surface IgM+ immature B cells emigrate from the BM via the blood stream to the spleen and finally differentiate into conventional mature follicular B (FoB) cells and marginal zone (MZ) B cells. READ MORE