Search for dissertations about: "B1 and B2 receptors"

Showing result 1 - 5 of 10 swedish dissertations containing the words B1 and B2 receptors.

  1. 1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    University dissertation from Experimentel medicinsk vetenskap, Lunds Universitet

    Author : Caroline Sandén; Lunds universitet.; Lund University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Abstract : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. READ MORE

  2. 2. Inflammation, kinins, and kinin receptors

    University dissertation from Institutionen för kliniska vetenskaper, Lunds universitet

    Author : Sara Bengtson; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Evidence is accumulating that the pathogenesis of many diseases is triggered by inappropriate inflammatory responses. These serious complications may occur when the tightly regulated inflammatory network is out of balance and it is now clear that this can eventually cause substantial harm to own cells and tissues. READ MORE

  3. 3. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    University dissertation from Laboratory of Clinical and Experimental Allergy Research, Department of Otorhinolaryngology, Institute of Clinical Science, Malmö University Hospital, Lund University, Sweden

    Author : Yaping Zhang; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Abstract : Popular Abstract in Swedish Astma är en sjukdom som karakteriseras av upprepade anfall av andningssvårigheter, orsakade av kramp, slemhinnesvullnad och segt sekret i luftvägarna. Den finns beskriven i texter redan från det antika Grekland och rapporteras idag vara en sjukdom med utbredning över hela vårt klot. READ MORE

  4. 4. Effects of Inflammatory Mediators on Pulmonary Airways

    University dissertation from Medicinska fakulteten, Lunds universitet

    Author : Ofir Bachar; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Abstract : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. READ MORE

  5. 5. Evolution and Pharmacology of Receptors for Bradykinin and Neuropeptide Y in Vertebrates

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Torun Bromée; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Pharmacology; Evolution; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi;

    Abstract : The bradykinin and neuropeptide Y (NPY) receptors belong to the superfamily of G-protein coupled receptors (GPCRs). The GPCRs form the largest class of therapeutic targets and it is therefore of great interest to investigate the pharmacological properties, functions and evolution of these receptors. READ MORE