Search for dissertations about: "BRANCHED RNA"

Showing result 1 - 5 of 6 swedish dissertations containing the words BRANCHED RNA.

  2. 1. Nanostructured surfaces created by the interactions of dendrimers and oppositely charged amphiphiles

    Author : Marianna Yanez; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PAMAM; Surfactant; SDS; Lipid; Bilayer; Model Biomembrane; Nucleolipid; DLPA; DLPU; DNA; RNA; Neutron Reflectometry; Poly amidoamine ; Interface; Adsorption; Polyelectrolyte;

    Abstract : The research described in this thesis aims to understand the interactions between cationic poly(amidoamine) (PAMAM) dendrimers and small oppositely charged amphiphiles at the solid-liquid and air-liquid interfaces in relation to the bulk solution behavior. There is high interest in PAMAM dendrimers because they are well-defined polymers with a hierarchical architecture which makes them promising materials as nanocapsules and gene vectors. READ MORE

  4. 2. Studies on nucleic acids chemistry

    Author : Nitin Puri; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioorganic chemistry; Bioorganisk kemi; Bioorganic chemistry; Bioorganisk kemi; bioorganisk kemi; Biorganic Chemistry;

    Abstract : This thesis is divided into three parts: Part 1: Synthesis and conformational analysis of cyclic RNAs, and comparison with lariat RNAs modelling the lariat formed during processing of Group II and Nuclear pre-mRNA. Synthesis of a hexameric lariat RNA model with a tetranucleotidyl "2' → 5' loop" and a dinucleotidyl "3'-tail" has been accomplished. READ MORE

  5. 3. Guardians of the genome : Connecting chromatin structure and genome integrity in Saccharomyces cerevisiae

    Author : Stefanie Lena Bauer; Stefan U. Åström; Brian Luke; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Branched DNA structures arise during recombination and during other DNA repair processes such as repair of stalled replication forks. One branched structure, the Holliday Junction (HJ), is a four-way junction that can connect sister chromatids or homologous chromosomes. We show a physical interaction between the HJ-cleaving enzyme Yen1 and Uls1. READ MORE

  6. 4. Polyester dendrimers for biomedical applications

    Author : Patrik Stenström; Michael Malkoch; Javier de la Mata; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Dendrimers are perfectly defined and highly branched large molecules with a high density of functional groups that makes them interesting for a variety of biomedical applications such as drug delivery, theranostics and as antimicrobials. Their synthesis can be complicated, time-consuming and expensive which has been an obstacle to their success. READ MORE

  7. 5. Functional screening and molecular characterisation of small proteins

    Author : Dörte Schlesinger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Proteins are one of the main drivers of cellular function. Most known proteins constitute various hundred amino acids, but growing evidence suggests that additionally thousands of short open reading frames (sORFs) are translated, posing the exciting possibility that many small unknown proteins are yet to be discovered. READ MORE