Search for dissertations about: "Bactec"

Found 5 swedish dissertations containing the word Bactec.

2. 1. Drug-resistant Mycobacterium tuberculosis in Estonia

   Author : Annika Krüüner; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Tuberculosis; Estonia; M. tuberculosis; drug resistance; MDR-TB; Beijing genotype; cross-resistance; kanamycin; amikacin; rrs mutations; 16S rRNA; exposure; nosocomial transmission; mycobacterial persistence; re-infection; DST; second-line drugs; Bactec; 460; DNA fingerprinting; spoligotyping;

   Abstract : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. READ MORE

4. 2. Tuberculosis : diagnosis and drug susceptibility testing where resources are scarce

   Author : Kristian Ängeby; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Tuberculosis; diagnosis; microscopy; drug susceptibility testing; low-income countries;

   Abstract : Background: Tuberculosis remains a major global public health problem. Not surprisingly, most cases of this disease occur in poor countries and an increasing number of patients harbor drug - resistant bacteria. The cornerstone of bacteriological diagnosis of tuberculosis is direct sputum smear microscopy. READ MORE

5. 3. Drug resistance in mycobacterium tuberculosis

   Author : Getahun Abate; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Multidrug-resistance; tuberculosis; cefepime; moxicillin-clavulanate; ethambutol; WIT; rifampicin; isoniazid; katG;

   Abstract : Drug-resistant tuberculosis is a global public health problem. This investigation was performed to find ways of improving regimens that could be used for the treatment of drug- and multidrug-resistant TB and also to find a rapid method of diagnosis of drug resistant TB, particularly MDR-TB. Among 107 isolates of M. READ MORE

6. 4. Rapid detection of drug resistance and genetic characterisation of Mycobacterium tuberculosis isolates in Honduras

   Author : Senia Rosales; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: New challenges for tuberculosis (TB) control are emerging in the 21st century. The deadly combination TB/HIV as well as the development and spread of new forms of drug resistance are some examples. In this context, the timely detection of TB cases, especially of those with resistant TB is important. READ MORE

7. 5. Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type

   Author : Jim Werngren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The increasing rates of multidrug resistant tuberculosis (MDR-TB) worldwide, are seriously threatening the TB control efforts. The present thesis was aimed at increasing the knowledge about the role of different factors, such as the development of drug resistance and the efficacy of drug susceptibility assessments, in the problem with MDR-TB. READ MORE