Search for dissertations about: "Basic leucine zipper"

Showing result 1 - 5 of 8 swedish dissertations containing the words Basic leucine zipper.

  1. 1. The p97 ATPase and the Drosophila Proteasome Protein Unfolding and Regulation

    University dissertation from Stockholm : Department of Molecular Biology and Functional Genomics, Stockholm University

    Author : Kristian Björk Grimberg; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteasome; ubiquitin; p97; unfolding; regulation; RNAi screen; high-throughput screen; cnc; basic leucine zipper; transcription factors; proteasome inhibition; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : For all living systems, there is a requirement to recycle and regulate proteins. In eukaryotic organisms this is accomplished by the proteasome. The p97 ATPase is another highly conserved and essential complex present throughout the eukaryotic cell. READ MORE

  2. 2. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Per Antonson; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

    Abstract : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipperclass of transcription factors with a total of 6 members having been identified in this familyso far. This gene family has been mainly implicated in regulation of cell specific geneexpression and differentiation. READ MORE

  3. 3. bHLH transcription factors in differentiating neuroblastoma cells

    University dissertation from Anna Grynfeld, Jumkilsg 18B, 752 18 Uppsala, Sweden

    Author : Anna Grynfeld; Lunds universitet.; Lund University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bHLH; Neuroblastoma; HES-1; HASH-1; N-Myc; differentiation; Mad; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Popular Abstract in Swedish Under fosterutvecklingen är det viktigt att alla kroppens celltyper kommer till rätt plats vid rätt tidpunkt. Det är också viktigt att cellerna mognar och delar sig under kontrollerade former. Då dessa processer inte fungerar, kan missbildningar eller cancer uppstå. READ MORE

  4. 4. Myc oncoprotein-cofactor interactions : Function, regulation and targeting

    University dissertation from Stockholm : Karolinska Institutet, Department of Microbiology, Tumor and Cell Biology

    Author : Karin Ridderstråle; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The members of the Myc-family of proto-oncoproteins c-Myc, N-Myc and L-Myc are transcription factors exerting their effect via protein-protein interactions. The Myc proteins are basic-helix-loop-helix-leucine-zipper (bHLHzip) transcription factors, which after heterodimerization with their obligatory partner Max, bind to E-boxes in target gene promoters and regulate the expression of 10-15% of all genes by the recruitment of different cofactors. READ MORE

  5. 5. Transcriptional regulation of differentiation markers in the distal lung epithelium : A role for C/EBP factors

    University dissertation from Stockholm : Karolinska Institutet, Department of Medical Nutrition

    Author : Tobias Cassel; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung; C EBP; Cellular Differentiation; Clara Cell Secretory Protein; Development; Gene Expression; Transcriptional Regulation; CYP21B1; Promoter; Synergism; Nkx2.1;

    Abstract : Late lung development is characterised by extensive cellular differentiation, resulting in a variety of specialised epithelial cell types. Although much is known of the extracellular signalling involved in lung morphogenesis, less is currently known of the intracellular developmental mechanisms that govern cellular differentiation. READ MORE