Search for dissertations about: "Bcl-X"

Found 4 swedish dissertations containing the word Bcl-X.

  2. 1. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

    Author : Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. READ MORE

  4. 2. Studies on the Bcl-2 Family of Apoptosis Regulators in the Nervous System

    Author : Susanne Hamnér; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Bcl-2; Bcl-w; Bad; Apoptosis; Nervous system; Cerebellar granule cells; Sympathetic neurons; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Apoptosis is a type of cell death with a specific morphology and molecular program, which is essential for the development of the nervous system. However, inappropriate cell death has been implicated in several neurodegenerative diseases. READ MORE

  5. 3. Regulation of apoptosis in human multiple myeloma

    Author : Helena Spets; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; apoptosis; multiple myeloma; IL-6; Bcl-2; Fas; dexamethasone; IGF-I; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Multiple myeloma (MM) is a clonal expansion of malignant plasmablasts-plasma cells in the bone marrow. MM is slowly proliferating and an increased resistance to apoptosis may be crucial for the tumor progression. READ MORE

  6. 4. Molecular mechanisms involved in the growth of human uterine leiomyomas

    Author : Xuxia Wu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human uterine leiomyomas; myometrium; the menstrual cycle; estrogen; progesterone; cellular proliferation; apoptosis; oncogene; growth factor; growth factor receptor.;

    Abstract : Human uterine leiomyomas (fibroids) are benign neoplasms arising from uterine smooth muscle cells, and are suggested to be sex steroid dependent. The aim of this study was to investigate the molecular mechanisms by which sex steroids, mainly estrogen and progesterone, influence the growth of Ieiomyomas. READ MORE