Search for dissertations about: "Bettina Gruhne"

Found 1 swedish dissertation containing the words Bettina Gruhne.

2. 1. Role of latent EBV genes in the induction of genomic instability in Burkitt’s lymphoma

   Author : Bettina Gruhne; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Epidemiological and molecular evidence link Epstein-Barr virus (EBV) infection to a variety of lymphoid and epithelial malignancies but the contribution of the virus to tumorigenesis is unclear. Genomic instability, defined by the establishment of a mutator phenotype and characterized by the occurrence of non-clonal chromosomal aberrations, excessive DNA damage and defects in DNA repair, is the hallmark of malignant transformation. READ MORE