Search for dissertations about: "Bioactive Fungal Metabolites"

Found 2 swedish dissertations containing the words Bioactive Fungal Metabolites.

  1. 1. Studies of New Bioactive Fungal Metabolites

    University dissertation from Rudong Shan, Organic Chemistry 2, Lund Institute of Technology, Center for Chemistry and Chemical Engineering, P. O. Box 124, S-221 00 Lund, Sweden

    Author : Rudong Shan; Lunds universitet.; Lund University.; [1996]
    Keywords : lachnumon; papyracillic acid; mycorrhizin; nematicidal and antimicrobial activity; Lachnum papyraceum; triprenyl phenols; Albatrellus ovinus; dopamine D1 receptor; salicylic acid derivatives; TBPS binding; GABAA receptor; Fungal metabolites; CNS activity; Organic chemistry; Organisk kemi; Kemi; Chemistry;

    Abstract : A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of the fungus HA 137-89 yielded two new inhibitors of the binding of 35S-TBPS to the brain GABAA/benzodiazepine chloride channel receptor complex. READ MORE

  2. 2. Novel biologically active compounds by semisynthesis with fungal metabolites

    University dissertation from Dept. of Bioorganic Chemistry, P.O. Box 124, SE-221 00 Lund, Sweden

    Author : Johan Eriksson Bajtner; Lunds universitet.; Lund University.; [2004]
    Keywords : Organic chemistry; Organisk kemi; bioactive compounds.; isovelleral; podoscyphic acid; Natural products; semisynthesis; Kemi; Chemistry;

    Abstract : Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. READ MORE