Search for dissertations about: "Bioactive Fungal Metabolites"

Found 5 swedish dissertations containing the words Bioactive Fungal Metabolites.

  1. 1. Studies of New Bioactive Fungal Metabolites

    University dissertation from Rudong Shan, Organic Chemistry 2, Lund Institute of Technology, Center for Chemistry and Chemical Engineering, P. O. Box 124, S-221 00 Lund, Sweden

    Author : Rudong Shan; [1996]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; papyracillic acid; lachnumon; mycorrhizin; nematicidal and antimicrobial activity; Lachnum papyraceum; triprenyl phenols; Albatrellus ovinus; dopamine D1 receptor; salicylic acid derivatives; TBPS binding; GABAA receptor; Fungal metabolites; CNS activity; Organic chemistry; Organisk kemi;

    Abstract : A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of the fungus HA 137-89 yielded two new inhibitors of the binding of 35S-TBPS to the brain GABAA/benzodiazepine chloride channel receptor complex. READ MORE

  2. 2. Novel biologically active compounds by semisynthesis with fungal metabolites

    University dissertation from Department of Bioorganic Chemistry, Lund University

    Author : Johan Eriksson Bajtner; Lunds universitet.; Lund University.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; bioactive compounds.; isovelleral; podoscyphic acid; Natural products; semisynthesis;

    Abstract : Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. READ MORE

  3. 3. Analysis of Secondary Metabolites from Aspergillus fumigatus and Penicillium nalgiovense Antimicrobial Compounds from Filamentous Fungi Isolated from Extreme Environments

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Stefan Svahn; Uppsala universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aspergillus fumigatus; Penicillium nalgiovense; secondary metabolites; invasive aspergillosis; elicitation; gliotoxin; bis methyl gliotoxin; amphotericin B; Pharmacognosy; Farmakognosi;

    Abstract : This thesis describes the cultivation and extraction of filamentous fungi isolated from extreme environments in the search for new antibiotic compounds. Filamentous fungi are a rich source of medicines including antibiotics, and it is believed that many currently unknown fungal species and bioactive fungal metabolites remain to be discovered. READ MORE

  4. 4. Biochemical Interactions of Some Saproxylic Fungi

    University dissertation from Sundsvall : Mid Sweden University

    Author : Joel Ljunggren; Mittuniversitetet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biologically active compounds; bioactive; fungi-fungi interaction; fungi co-culture; extracellular amino acids.;

    Abstract : Interactions are all around us, and as humans we may use words and gestures to communicate our intentions. At the micro level of fungi, communications are replaced by chemical signals and structure. READ MORE

  5. 5. Systems Biology of the Secondary Metabolism in Filamentous Fungi

    University dissertation from Chalmers University of Technology

    Author : Jens Christian Froslev Nielsen; Chalmers tekniska högskola.; Chalmers University of Technology.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Next-generation sequencing; cell factories; Penicillium; secondary metabolism; filamentous fungi; genomics; antibiotics; secondary metabolites; systems biology;

    Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE