Search for dissertations about: "Biochemistry towards Bioinformatics"

Showing result 1 - 5 of 41 swedish dissertations containing the words Biochemistry towards Bioinformatics.

2. 1. Formalizing life : Towards an improved understanding of the sequence-structure relationship in alpha-helical transmembrane proteins

   Author : Håkan Viklund; Arne Elofsson; Kimmen Sjölander; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; protein; topology; hidden Markov model; prediction; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

   Abstract : Genes coding for alpha-helical transmembrane proteins constitute roughly 25% of the total number of genes in a typical organism. As these proteins are vital parts of many biological processes, an improved understanding of them is important for achieving a better understanding of the mechanisms that constitute life. READ MORE

4. 2. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows

   Author : Ufuk Kirik; Institutionen för immunteknologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cancer; proteome profiling; bioinformatics; pathway analysis; mass spectrometry; Quantitative proteomics;

   Abstract : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. READ MORE

5. 3. The labyrinth of protein classification: a pipeline forselection and classification of biological data

   Author : Benedetta Pelosi; Neus Visa; Antonio Barragan; Stefan Jansson; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pipeline; filtering; machine learning; deep learning; computational biology; bioinformatics; mitochondrial metabolism; carotenoid biosynthesis; orthologs; protein analyses; statistics; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics; statistik; Statistics;

   Abstract : Recent progress in fundamental biological sciences and medicine has considerably increased the quantity ofdata that can be studied and processed. The main limitation now is not retrieving data, but rather extractinguseful biological insights from the large datasets accumulated. READ MORE

6. 4. Predicting the route: from protein sequence to sorting in eukaryotic cell

   Author : Marco Salvatore; Arne Elofsson; Norman Davey; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; eukaryotic cell; sorting signals; subcellular localisation; machine learning; biological sequence analysis; bioinformatics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : Proteins need to be localised in the correct compartment of a eukaryotic cell to function correctly. Therefore, a protein needs to be transported to the right location. Specific signals present in the protein sequence direct proteins to different subcellular localisations. READ MORE

7. 5. Development of Molecular Biology and Bioinformatics Tools : From Hydrogen Evolution to Cell Division in Cyanobacteria

   Author : Fernando Lopes Pinto; Peter Lindblad; Röbbe Wünschiers; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; hydrogen; RNA; bioinformatics; RT-PCR; RACE; transcription; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Molecular Biology; Molekylärbiologi;

   Abstract : The use of fossil fuels presents a particularly interesting challenge - our society strongly depends on coal and oil, but we are aware that their use is damaging the environment. Currently, this awareness is gaining momentum, and pressure to evolve towards an energetically cleaner planet is very strong. READ MORE