Search for dissertations about: "Biochemistry"

Showing result 1 - 5 of 1473 swedish dissertations containing the word Biochemistry.

  1. 1. Proteins of the Inter-α-inhibitor Family Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Aneta Kaczmarczyk; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE

  2. 2. On the Versatility of Microwave-Assisted Chemistry Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kristina M. Orrling; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microwave-assisted chemistry; malaria; aspartic protease; plasmepsin; PfPM4; PmPM4; PoPM4; PvPM4; inhibitor; unsaturated lactone; unsaturated lactam; unsaturated amide; lactam; Bestmann s ylide; ionic liquid; polymerase chain reaction; thermophilic enzyme; NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry; NATURVETENSKAP Kemi Organisk kemi Läkemedelskemi; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; biokemi; Biochemistry;

    Abstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE

  3. 3. DNA precursor biosynthesis-allosteric regulation and medical applications

    University dissertation from Umeå : Medicinsk kemi och biofysik

    Author : Reza Rofougaran; Umeå universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; DNA biosynthesis; ribonucleotide reductase; allosteric regulation; Trypanosoma brucei; adenosine kinase; nucleoside analogs; mitochondrial DNA; TWINKLE; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). READ MORE

  4. 4. Chromatin Remodeling by BRG1 and SNF2H Biochemistry and Function

    University dissertation from Stockholm : Wenner-Grens institut för experimentell biologi

    Author : Patrik Asp; Stockholms universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatin; chromatin remodeling; SWI SNF; ISWI; BRG1; SNF2H; Prp8; RNA; transcription; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi;

    Abstract : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. READ MORE

  5. 5. Selenoproteins in the Bovine Mammary Gland. Regulation of mRNA and Protein Expression

    University dissertation from Pure and Applied Biochemistry, Lund University

    Author : Katharina Bruzelius; Lunds universitet.; Lund University.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Food and drink technology; Livsmedelsteknik; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; milk; Natural science; cancer; prolactin; insulin; hydrocortisone; retinoic acid; MAC-T; northern blot; two-dimensional electrophoresis; bovine mammary gland; selenium; selenoprotein;

    Abstract : Selenium is a micronutrient that is essential for many important life processes due to the action of the specific selenoproteins containing one or more of the 21st amino acid, selenocysteine. Twenty-five selenoprotein genes have been found in the human genome but the function of many of them is not yet known. READ MORE