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Showing result 1 - 5 of 31 swedish dissertations matching the above criteria.

2. 1. Surviving the ratchet : Modelling deleterious mutations in asexual populations

   Author : Jonas Söderberg; Otto Berg; Laurence Loewe; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Theoretical biology; Population genetics; Stochastic modelling; Genome evolution; Muller s Ratchet; Genetics; Genetik; Organism biology; Organismbiologi; Biology; Biologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

   Abstract : One of the most unforgiving processes in nature is that of Muller's ratchet, a seemingly irreversible accumulation of deleterious mutations that all organisms have to deal with or face extinction. The most obvious way to avoid fitness collapse is recombination, though asexual populations usually do not have the luxury of recombining freely. READ MORE

4. 2. Evolution of symbiotic lineages and the origin of new traits

   Author : Daniel Tamarit; Siv G. E. Andersson; Lisa Klasson; Amparo Latorre; Julian Parkhill; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; symbiosis; host-association; Lactobacillus; Bifidobacterium; Rhizobiales; Bartonella; honeybees; ants; codon usage bias; genome architecture; genome organization; gene transfer agent; evolutionary genomics; comparative genomics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Abstract : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. READ MORE

5. 3. Expanding the Chlamydiae tree : Insights into genome diversity and evolution

   Author : Jennah E. Dharamshi; Thijs J. G. Ettema; Alexander Probst; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PVC superphylum; Chlamydiae; chlamydia; intracellular; symbiosis; endosymbiont; pathogen; marine sediment; sponge microbiome; metagenomics; uncultured microbial diversity; phylogenomics; microbial evolution; eukaryote evolution; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

   Abstract : Chlamydiae is a phylum of obligate intracellular bacteria. They have a conserved lifecycle and infect eukaryotic hosts, ranging from animals to amoeba. Chlamydiae includes pathogens, and is well-studied from a medical perspective. READ MORE

6. 4. Evolution of cellular complexity and other remarkable features in Gemmataceae : Complex bacterial lineages defy prokaryotic trends

   Author : Mayank Mahajan; Siv G. E. Andersson; James O. McInerney; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular evolution; Planctomycetes; Gemmataceae; functional organization; signalling; protein interaction; peptidoglycan; membranes; cell division; radiation tolerance; Pfam; SCOP; comparative genomics; protein architecture; domain shuffling and orthologous clustering; Bioinformatics; Bioinformatik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Abstract : Bacteria of the family Gemmataceae belong the phylum Planctomycetes and are remarkable because of their complex cellular architectures, previously considered to be traits exclusive to eukaryotes. This thesis provides clues to the atypical cell envelope, the enhanced radiotolerance and the amazing cellular complexity of these bacteria. READ MORE

7. 5. Multi-omics investigation into bacterial evolution

   Author : Karl Dyrhage; Siv Andersson; Dan I. Andersson; Jay Hinton; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; bacterial evolution; cellular complexity; comparative genomics; transcriptomics; proteomics; fructophilic lactic acid bacteria; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

   Abstract : The focus of this thesis is the investigation of the evolution and cellular processes of Tuwongella immobilis and Apilactobacillus kunkeei, two bacterial species with different levels of genomic and cellular complexity, using a multi-omics approach.In the first study we examined the proteome of T. READ MORE