Search for dissertations about: "Biologically active compounds"
Showing result 1 - 5 of 44 swedish dissertations containing the words Biologically active compounds.
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1. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels
Abstract : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. READ MORE
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2. Novel biologically active compounds by semisynthesis with fungal metabolites
Abstract : Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. READ MORE
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3. Biologically Interesting Compounds from Natural Sources
Abstract : Natural products have traditionally played a major role in the drug discovery process. Besides constituting extremely popular drugs in the market, and an ever-increasing source of interesting and novel chemical structures, they have also aided the characterization of many a pharmacological target. READ MORE
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4. Synthesis Towards Biologically Active Natural Products
Abstract : In 2005 two research groups independently reported the isolation of a series of structurally intriguing C-19 terpenolides from the plants Thapsia transtagana and Thapsia garganica. The compounds were shown to be potent inhibitors of the sarco/endoplasmic reticulum Ca2+-ATPases. READ MORE
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5. Biologically active terpenoids from Bolivian medicinal plants
Abstract : Pseudo-guaianolides represent a large group of sesquiterpene lactones exhibiting significant cytotoxic and anti-inflammatory activities. Their biological activities are due to a 훼-methylene-훾-lactone unit in their chemical structure, which reacts with free sulfhydryl groups of free cysteine via a Michael-addition. READ MORE