Search for dissertations about: "Biologics"

Showing result 1 - 5 of 24 swedish dissertations containing the word Biologics.

  2. 1. Biologics in Staphylococcus aureus arthritis

    Author : Abukar Ali; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; CTLA4-Ig; IL-1 Ra; anti-TNF therapy; mouse; septic arthritis;

    Abstract : The emergence of new type of drugs known as biologics has led to rapid disease improvements in many autoimmune arthritic patients. Nevertheless, most of these biologics are immunomodulators that may consequently increase the susceptibility of patients towards infections, such as septic arthritis. READ MORE

  4. 2. Strategies to improve and balance the expression levels of recombinant proteins in mammalian cell lines

    Author : Mona Moradi Barzadd; Johan Rockberg; Alan Dickson; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CHO; HEK293; Aggregation; Bispecific; Cancer assay; Cell line engineering; sulfatase; biologics; transcriptomic; Biotechnology; Bioteknologi;

    Abstract : Proteins are the building blocks of all living organisms enabling us to function and survive. There are more than 100,000 different proteins in the human body performing a variety of vital tasks. READ MORE

  5. 3. Effectiveness and costs of new medical technologies : register-based research in psoriasis

    Author : Jenny Norlin; Marcus Schmitt-Egenolf; Ulf Persson; Katarina Steen Carlsson; Lars-Åke Levin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; registers; EQ-5D; DLQI; PASI; biologics;

    Abstract : Psoriasis is a chronic, immunological and systemic disease with an estimated prevalence of about 2-3 percent. Psoriasis is associated with the joint disease psoriasis arthropathy. There are several treatments options available for psoriasis and patients with moderate to severe psoriasis generally need systemic agents. READ MORE

  6. 4. Impact of Drug Induced Remission in Rheumatoid Arthritis

    Author : Jon Thorkell Einarsson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid Arthritis; remission; remission maintenance; Biologics; Register research;

    Abstract : .... READ MORE

  7. 5. Assessing the Inventiveness of Bio-Pharmaceuticals under European and US Patent Law - A comparative study with special emphasis on DNA- and protein-related inventions

    Author : Timo Minssen; Juridiska institutionen; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; DNA; Proteins; Patents; USA; Europe; Biologics; Non-Obviousness; Inventive Step; Biotechnology; Comparative Law;

    Abstract : “The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. READ MORE