Search for dissertations about: "Biotechnology"
Showing result 11 - 15 of 1674 swedish dissertations containing the word Biotechnology.
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11. Engineering the Secretory Pathway for Recombinant Protein Secretion in Saccharomyces cerevisiae
Abstract : In the past few decades there has been an increasing demand of biopharmaceutical proteins in the market. Several types of cell factories are applied to produce different pharmaceutical proteins. READ MORE
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12. Metabolic Engineering of Recombinant Protein Production by Saccharomyces cerevisiae
Abstract : The yeast Saccharomyces cerevisiae is a widely used cell factory for the production of fuels, chemicals, and it also provides a platform for the production of many heterologous proteins of medical or industrial interest. In this thesis, random and rational approaches, such as vector design, host engineering, fermentation analysis, UV Mutation, coupled with high-throughput systems biology techniques (including whole genomic sequencing, microarray analysis and flux analysis) and integrated analysis (Reporter feature technique), were employed to engineer cellular properties more effectively and purposefully to construct cell factories for protein production. READ MORE
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13. How do biogas solutions influence the sustainability of bio-based industrial systems?
Abstract : Biomass is a valuable and limited resource that should be used efficiently. The potential of replacing fossil-based products with bio-based ones produced in biobased industrial systems is huge. One important aim of increasing the share of biobased products is to improve the sustainability of systems for production and consumption. READ MORE
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14. Design of solid dosage forms for mucosal vaccination - Investigations on the influence of excipients on product performance
Abstract : Most vaccines today are liquid formulations for parental administration. However, there are several drawbacks connected to these vaccines. Since injectable vaccines only induce systemic antibody responses, they are not effective against the various pathogens that affect mucosal surfaces with poor permeability for serum-derived antibodies, e.g. READ MORE
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15. Multiplexed antibody-based protein profiling in the pursuit of CSF biomarkers for neurodegenerative diseases
Abstract : There is a desire for a transition from generic treatments designed for the average patient, towards more individual-based precision medicine. An increased knowledge about disease pathophysiology on a molecular level would be beneficial for this transition. READ MORE