Search for dissertations about: "Blood coagulation"

Showing result 1 - 5 of 183 swedish dissertations containing the words Blood coagulation.

2. 1. Inflammation and immunothrombosis in cerebral cavernous malformation : Novel molecular targets for the treatment of an incurable disease

   Author : Maria Ascención Globisch; Peetra Magnusson; Elisabetta Dejana; Marie Jeansson; Anna Randi; Uppsala universitet; []
   Keywords : Cavernoma; Inflammation; Coagulation; Blood-brain-barrier; Blood; Hypoxia; Propranolol; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

   Abstract : Cerebral cavernous malformation (CCM) is a vascular disease that causes mulberry-like lesions (cavernomas) in the central nervous system (CNS). Cavernomas are fragile, leaky and prone to rupture which may cause symptoms such as epileptic seizures, focal neurological deficits and hemorrhagic strokes. CCM lesions can appear sporadically in 0. READ MORE

4. 2. Synthesis, Function, and Inactivation of Blood Coagulation Factor V

   Author : Kristoffer Sørensen; Malmö Klinisk kemi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; activated protein C; heparin; calcium binding; R2 haplotype; Blood Coagulation; Factor V; Clinical chemistry; Klinisk kemi;

   Abstract : Blood coagulation factor V (FV) is a 330 kDa plasma glycoprotein. Activated FV (FVa) is a non-enzymatic cofactor to activated Factor X in the activation of prothrombin that occurs during coagulation. READ MORE

5. 3. Regulation of Tissue Factor and Coagulation Activity : Translation Studies with Focus on Platelet-Monocyte Aggregates and Patients with Acute Coronary Syndrome

   Author : Christina Christersson; Agneta Siegbahn; Lars Wallentin; Jonas Oldgren; Ingebjorg Seljeflot; Uppsala universitet; []
   Keywords : Internal medicine; Myocardial infarction; Coagulation; Platelet-monocyte aggregates; Tissue factor; Thrombin inhibition; Invärtesmedicin;

   Abstract : Myocardial infarction (MI) is often caused by a disruption of an atherosclerotic plaque with activation of coagulation, platelets and inflammation. The aims were; to investigate whether the oral direct thrombin inhibitor, ximelagatran affected markers for coagulation, platelet and inflammation in a patient cohort with recent MI and if the coagulation markers could identify patients with increased risk of new ischemic events; to evaluate some of the mechanisms involved in formation of platelet-monocyte aggregates (PMAs). READ MORE

6. 4. Protamine, Platelet Function and Coagulation in Cardiac Surgery

   Author : Mattias Törnudd; Sören Berg; John-Peder Escobar Kvitting; Sofia Ramström; Joakim Alfredsson; Ulf Schött; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiopulmonary bypass; Protamine; Platelet function; Coagulation;

   Abstract : Bleeding is a serious and common complication in cardiac surgery. Complicated surgery together with alterations in hemostatic conditions from the use of cardiopulmonary bypass (CPB), presents challenges in how to preserve hemostasis in the patient.   CPB is thought to affect platelet function and coagulation in many ways. READ MORE

7. 5. Biomaterials and Hemocompatibility

   Author : Anna E. Engberg; Kristina Nilsson Ekdahl; Peter Zipfel; Linnéuniversitetet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement; Coagulation; Whole blood; Biomaterials; Polymers and Hemocompatibility; Immunology; Immunologi; Biomedical Sciences; Biomedicinsk vetenskap;

   Abstract : Biomaterials are commonly used in the medical clinic today; however, artificial materials can activate the cascade systems in the blood (complement-, coagulation-, contact- and fibrinolytic systems) as well as the platelets to various degrees. When an artificial surface comes in contact with blood, plasma proteins will be adsorbed to the surface within seconds. READ MORE