Search for dissertations about: "Burkitt Iymphoma"
Found 2 swedish dissertations containing the words Burkitt Iymphoma.
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1. p53 inactivation by point mutations and splice site mutations in human and mouse tumors
Abstract : The p53 tumor suppressor gene is frequently mutated in human tumors. p53 induces cell cycle arrest and/or apoptosis in response to cellular stress, such as DNA damage, hypoxia and certain activated oncogenes like c-myc. The status of p53 in Burkitt's Iymphoma (BL) cell lines was investigated. The majority of BL lines expressed mutated p53 protein. READ MORE
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2. Characteristics of EBV-infected B cell lines and B-CLL clones which determine their interaction with lymphocytes
Abstract : The results concerning T Iymphocyte mediated recognition of Epstein-Barr virus (EBV) carrying Burkitt Iymphoma (BL) cell lines and EBV-infected chronic Iymphocytic leukemia (CLL) B cells contribute to the understanding of the generally harmless host-EBV interaction and may be extrapolated to the fate of normal B cells after EBV infection. The phenotype of EBV negative BL lines resembles resting B cells. READ MORE