Search for dissertations about: "CAAT"

Found 5 swedish dissertations containing the word CAAT.

  2. 1. Structure and expression of the TP and EP1 prostanoid receptor genes

    Author : Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Abstract : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. READ MORE

  4. 2. Isolation and characterization of genes within the region for multiple endocrine neoplasia type 1 on chromosome 11q13

    Author : Jacob Lagercrantz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Multiple Endocrine Neoplasia type 1 MEN1 ; Chromosome 11q13; Phospholipase C Beta 3 gene PLCB3 ; Phospholipase C Beta 3 Neighbouring Gene PNG ; Vascular Endothelial Growth Factor VEGF ; VEGF Related Factor gene VRF .;

    Abstract : This thesis summarizes the investigations of three genes isolated from the locus for multiple endocrine neoplasia type 1 (MEN1) within the chromosomal region 11q13. As a common strategy for all three genes, the cDNA was sequenced, the genomic structure characterized, and the expression pattern analyzed by Northern blotting on human tissues and by in situ RNA hybridization on slides from rodent embryos. READ MORE

  5. 3. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

    Author : Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
    Keywords : Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

    Abstract : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. READ MORE

  6. 4. Human insulin-like growth factor binding protein-4 and -6 : gene structure and transcription regulation

    Author : Henric Zazzi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : IGF binding proteins IGFBP ; DNA sequencing; chromosomal localization; gene expression; Sp I; NF-kappa-B; methylation;

    Abstract : Insulin-like growth factors (IGF-I and IGF-II) are among the more abundant growth factors isolated from bone tissue and are synthesized by various bone cells including osteoblasts. The activity of IGFs is controlled by a family of binding proteins (IGFBPs) divided into subfamilies depending on their individual affinity for IGFs. READ MORE

  7. 5. Type IV collagen : regulation of COL4A1 and COL4A2 genes and gene therapy of Alport syndrome

    Author : Pirkko Kortteinen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adenovirus; Alport syndrome; basement membrane; bidirectional promoter; collagen; gene regulation; gene therapy; promoter analysis; kidney gene transfer; organ perfusion; type IV collagen;

    Abstract : Type IV collagen is an important structural protein in basement membranes, which am thin sheet-like structures located between organized tissues and the connective tissue. Type IV collagen is composed of six genetically different [alpha] chains. READ MORE