Search for dissertations about: "CBFâ"

Found 1 swedish dissertation containing the word CBFâ.

2. 1. Structure-function relationships of the human Runx1 transcription factor

   Author : Magnus Wolf-Watz; KTH; []
   Keywords : Runx1; Runt domain; CBFâ; transcription; leukemia; protein structure; protein dynamics;

   Abstract : Runx transcription factors contain a DNA-binding andtransactivating α-subunit and a β-subunit (CBFβ)that serves to increase the DNA binding affinity of theα-subunit. The DNA binding domain of Runx proteins isnamed the Runt homology domain (RD) after its strong sequencehomology to theDrosophilaprotein Runt. READ MORE