Search for dissertations about: "CHROMATIN MODEL"

Showing result 1 - 5 of 125 swedish dissertations containing the words CHROMATIN MODEL.

  2. 1. Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function

    Author : Patrik Asp; Ann-Kristin Östlund Farrants; Anthony Imbalzano; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatin; chromatin remodeling; SWI SNF; ISWI; BRG1; SNF2H; Prp8; RNA; transcription; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Chromatin is a highly dynamic, regulatory component in the process of transcription, repair, recombination and replication. The BRG1 and SNF2H proteins are ATP-dependent chromatin remodeling proteins that modulate chromatin structure to regulate DNA accessibility for DNA-binding proteins involved in these processes. READ MORE

  4. 2. The interplay of transcription and chromatin regulation during embryonic development

    Author : George Hunt; Mattias Mannervik; Eileen Furlong; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription; chromatin; chromatin-modifiers; p300 CBP; Polycomb repression; promoter proximal Pol II pausing; molekylär biovetenskap; Molecular Bioscience;

    Abstract : A fascinating aspect of multicellular development is the production of diverse cell types from an identical DNA genome, which depends on the ability to express different complements of genes across space and time. This thesis tries to address how the genome, within the chromatin structure that envelops it, is regulated to direct this complex process. READ MORE

  5. 3. Transcription regulation across levels of chromatin organization

    Author : Roshan Vaid; Mattias Mannervik; Goncalo Castelo-Branco; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transcription; chromatin; epigenetics; Drosophila; embryo development; molekylär biovetenskap; Molecular Bioscience;

    Abstract : With advancements in high-throughput sequencing and high-resolution microscopy techniques, the significance of genome organization in transcription regulation is rapidly unveiling. Nonetheless, we are yet far from completely understanding this key relationship. READ MORE

  6. 4. RNA-based mechanisms of chromatin and gene regulation

    Author : Jordi Planells Rodrigo; Neus Visa; Simon Elsässer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gene regulation; chromatin; non-coding RNAs; genome-wide studies; Drosophila melanogaster; ADAR3; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Cells regulate gene expression in a particular spatio-temporal manner by executing specific transcriptional programs. The different transcriptional programs allow the generation of the different cell types in multicellular organisms and mediate particular cellular responses to external cues such as viral infections. READ MORE

  7. 5. Epigenetic Regulation of Higher Order Chromatin Conformations and Gene Transcription

    Author : Anita Göndör; Reinald Fundele; Thomas Graf; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Genomic imprinting; Chromatin; Epigenetics; Cancer; Developmental biology; Utvecklingsbiologi;

    Abstract : Epigenetic states constitute heritable features of the chromatin to regulate when, where and how genes are expressed in the developing conceptus. A special case of epigenetic regulation, genomic imprinting, is defined as parent of origin-dependent monoallelic expression. READ MORE