Search for dissertations about: "COX inhibitor"
Showing result 1 - 5 of 47 swedish dissertations containing the words COX inhibitor.
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1. Developmental disturbances of the embryo in diabetic pregnancy
Abstract : Maternal diabetes during pregnancy constitutes an increased risk for congenital malformation in the offspring. Previous studies have suggested that diabetic embryopathy is associated with an excess of reactive oxygen species (ROS) as well as with a disturbance of prostaglandin (PG) metabolism. READ MORE
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2. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response
Abstract : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. READ MORE
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3. Prostaglandin E2 in Brain-mediated Illness Responses
Abstract : We are unceasingly exposed to potentially harmful microorganisms. The battle against threatening infectious agents includes activation of both the innate and of the adaptive immune systems. READ MORE
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4. Inhaled Nitric Oxide Therapy : Non-response and Rebound Response
Abstract : Therapeutic inhaled nitric oxide (INO) has proved beneficial in patients with pulmonary hypertension. However, around 30-40% of the patients are non-responders to this therapy, and a life-threatening rebound response may occur during attempts to withdraw INO. READ MORE
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5. An integrative strategy for targeted evaluation of biomarker expression in non-small cell lung cancer
Abstract : Despite improvements in therapy, the prognosis for non-small cell lung cancer (NSCLC) patients remains poor, and cure is only possible in localized tumors after surgical resection. A new generation of targeted cancer drugs has led to the expectation that lung cancer therapy can be significantly improved, but these drugs are today only an option in a small subset of NSCLC patients, and their effect is temporary. READ MORE