Search for dissertations about: "CYP4A"

Found 2 swedish dissertations containing the word CYP4A.

  1. 1. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kerstin Lundell; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. READ MORE

  2. 2. Cytochrome P450 enzymes in the biosynthesis and metabolism of bile acids and active forms of vitamin D

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Zufan Araya; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; PHARMACY Biopharmacy; FARMACI Biofarmaci; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : Cytochrome P450 enzymes catalyzing hydroxylations in the biosynthesis and metabolism of bile acids and active forms of vitamin D3 were studied.A microsomal cytochrome P450 enzyme with a molecular mass of 53 kDa, catalyzing the 6α-hydroxylation of taurochenodeoxycholic acid was purfied from pig liver microsomes and characterized with respect to catalytic and electrophoretic properties as well as polyclonal antibodies. READ MORE