Search for dissertations about: "Caenorhabditis elegans"

Showing result 1 - 5 of 44 swedish dissertations containing the words Caenorhabditis elegans.

  2. 1. Regulation of energy balance in Caenorhabditis elegans 

    Author : Ming Sheng; Simon Tuck; Lars Nilsson; Carina Holmberg-Still; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; C.elegans; fat metabolism; S6 Kinase; FT-IR; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Abstract : Obesity is a medical condition in which excess body fat has been accumulated. It is most commonly caused by imbalance between energy intake and energy expenditure (lack of physical activity and lower metabolic rate, etc.). READ MORE

  4. 2. Oxygen sensing in Caenorhabditis elegans

    Author : Lina Zhao; Changchun Chen; Simon Tuck; Helena Edlund; Marc Pilon; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; C. elegans; acute hypoxia; G-protein; mitochondrial ROS; neuropeptide; GPCR;

    Abstract : Sufficient supply of oxygen (O2) to tissue is essential for survival of aerobicanimals. In mammals, there are constant homeostatic regulation mechanisms that act on different time scales to maintain optimal O2 delivery to tissues. The ability to detect and respond to acute oxygen shortages is indispensable to aerobic life. READ MORE

  5. 3. The control of growth and metabolism in Caenorhabditis elegans

    Author : Josefin Friberg; Simon Tuck; Cathy Savage-Dunn; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TGFβ; insulin; collagen; p70 S6K; metabolism; growth; dauer; Caenorhabditis elegans; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The control of growth is a poorly understood aspect of animal development. This thesis focuses on body size regulation in Caenorhabditis elegans, and in particular, how worms grow to a certain size. In C. elegans, a key regulator of size is the TGFβ homologue DBL-1. READ MORE

  6. 4. Studies on lipid transport and extracellular vesicle production in Caenorhabditis elegans ciliated neurons

    Author : Shapour Rahmani; Simon Tuck; Jonathan D. Gilthorpe; Anders Olsen; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; C. elegans; cilia; extracellular vesicles; tat; phospholipid translocase; P4-family ATPase;

    Abstract : The cilium is a protrusion of cell membrane. Both the protein and lipid contents of cilia are different from those of other parts of the cell membrane. While the transport of proteins into and out of cilia has been intensively studied, much less is known about how the lipid content of ciliary membranes is regulated. READ MORE

  7. 5. Adaptation and plasticity within and across generations

    Author : Zuzana Sekajova; Martin Lind; Lesley Lancaster; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phenotypic plasticity; nongenetic inheritance; environmental variation; Caenorhabditis elegans; Caenorhabditis remanei; life history; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology;

    Abstract : The environment is seldom stable but often changes from one state to another and in order to survive and reproduce organisms need to respond to those changes. If the change is fast, genetic adaptations may not evolve quickly enough and organisms must adopt other strategies, such as phenotypic plasticity. READ MORE