Search for dissertations about: "Cancer chemoprevention"

Showing result 1 - 5 of 8 swedish dissertations containing the words Cancer chemoprevention.

  2. 1. The effects of flaxseed and tamoxifen on the inflammatory microenvironment in normal breast tissue and in breast cancer

    Author : Gabriel Lindahl; Charlotta Dabrosin; Signe Borquist; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; inflammation; chemoprevention; tamoxifen; phytoestrogens; flaxseed; enterolactone; interleukins; osteopontin; chemokines; matrix metalloproteases; microdialysis;

    Abstract : Breast cancer is the most common cancer among women worldwide today. Nearly 9000 women are diagnosed with breast cancer in Sweden yearly and despite advantages in diagnostics and treatments approximately 1400 women still die from their disease every year. READ MORE

  4. 2. Prostanoids and colorectal cancer

    Author : Annika Gustafsson Asting; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer prostanoid receptors cyclooxygenase PGE2 transcription factors;

    Abstract : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. READ MORE

  5. 3. Drug repositioning in chemoprevention of colorectal cancer

    Author : Naiqi Zhang; Allmänmedicin och klinisk epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug repositioning; Colorectal cancer CRC ; Pharmacoepidemiology; Chemoprevention; Melatonin; Proguanil; Atovaquone; Selective serotonin reuptake inhibitor SSRI ;

    Abstract : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. READ MORE

  6. 4. A study of two major challenges in prostate cancer : effective chemo-prevention and overcoming resistance to hormonal and chemotherapy

    Author : Yuanjun Ma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : For men, over the course of a lifetime the risk of developing prostate cancer is 1 in 9. Both the illness itself and treatment affect quality of life in multiple aspects, including urinary problems, pain, and sexual dysfunction. READ MORE

  7. 5. Myc-induced Lymphomagenesis : In vivo assessment of downstream pathways

    Author : Sara Rimpi; Jonas Nilsson; Juha Klefström; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Myc; lymphomagenesis; Aurora kinases; polyamine; glycolysis; targeting; mouse models of cancer; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Myc oncogenes encode transcription factors that bind to E-box sequences in DNA, driving the expression of a large number of target genes and are deregulated in approximately 70% of human cancers. Deregulated Myc expression cause enhanced proliferation (which is counteracted by apoptosis), angiogenesis and cancer. READ MORE