Search for dissertations about: "Cancer of unknown primary"

Showing result 1 - 5 of 63 swedish dissertations containing the words Cancer of unknown primary.

  2. 1. Computational exploration of cancer genomes

    Author : Joakim Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer genomics; Transcriptomics; Driver genes; Copy number changes; Immunogenomics; Cancer of unknown primary; Uveal melanoma;

    Abstract : Cancer evolves due to changes in DNA that give a cell an advantage at the expense of the remaining organism. These alterations range from individual base substitutions to broad losses or duplications of chromosomal material. READ MORE

  4. 2. Aspects of Progression in Breast Carcinoma : from ductal carcinoma in situ to invasive cancer

    Author : Wenjing Zhou; Fredrik Wärnberg; Marie-Louise Fjällskog; Carl Blomqvist; Malin Sund; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; progression; ductal carcinoma in situ; breast cancer; Medicinsk vetenskap; Medical Science;

    Abstract : In the past decades our knowledge concerning breast cancer progression from ductal carcinoma in situ (DCIS) to invasive cancer has grown rapidly. However, molecular factors driving the progression are still largely unknown. READ MORE

  5. 3. Cellular Effects of Cystatins

    Author : Samar Hunaiti; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystatin C; Cystatin D; Galectin-1; Puncta assay; HoloMonitor; Cancer cells; Apoptosis; Cathepsin C;

    Abstract : The exact cellular functions of cystatins are still unknown, and the molecular mechanism leading to their internalization into cells is not yet fully understood. Commonly the cystatins are known to inhibit human lysosomal cysteine proteases (cysteine cathepsins) and it is supposed that this is their primary physiological role. READ MORE

  6. 4. Mechanisms for immune escape in epithelial ovarian cancer

    Author : Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. READ MORE

  7. 5. Platelets – Multifaceted players in tumor progression and vascular function

    Author : Yanyu Zhang; Anna-Karin Olsson; Gertraud Orend; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Abstract : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. READ MORE