Search for dissertations about: "Capillary electrophoresis"

Showing result 6 - 10 of 132 swedish dissertations containing the words Capillary electrophoresis.

  2. 6. Bioanalysis using capillary electrophoresis and mass spectrometry : Applied on proteins, protein nanofibrils and polyvinyl alcohol microbubbles

    Author : Leila Josefsson; Åsa Emmer; Ulrika Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; : amyloid; capillary electrophoresis; contrast agents; detection; human blood plasma; ionic liquids; mass spectrometry; microbubbles; polyvinyl alcohol microbubbles; protein nanofibrils; proteins; Kemi; Chemistry;

    Abstract : The sequencing of the genome of various species, including the human species, have led to increased understanding about how a protein structure is generated, and how specific structures are related to the proteins’ functionality. In paper I and II of this thesis, the folding of proteins in vitro to form hierarchical nanostructures, which in vivo often have a pathological effect, have been studied. READ MORE

  4. 7. Electrochemical Methods for Drug Characterisation and Transdermal Delivery : Capillary Zone Electrophoresis, Conductometry, and Iontophoresis

    Author : Nadia Merclin; Per Hansson; Sven Engström; Arto Urtti; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Capillary zone electrophoresis; precision conductometry; iontophoresis; passive diffusion; lidocaine; ALA; ALA-ester derivatives; sponge phase; carbopol gel; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Abstract : This thesis concerns the development and utilisation of techniques for characterisation and transdermal delivery of various systems for pharmaceutical applications.The degree of dissociation of drug molecules and the mobilities of the different species formed are essential factors affecting the rate of drug delivery by iontophoresis. READ MORE

  5. 8. Separation of Proteins with Capillary Electrophoresis in Coated Capillaries with and without Electroosmosis : Studies on Zone Broadening and Analytical Performances

    Author : Sheila Mohabbati; Douglas Westerlund; Bo Karlberg; Uppsala universitet; []
    Keywords : Pharmaceutical chemistry; Capillary electrophoresis; capillary coatings; proteins; zone broadening; zone sharpening; efficiency; resolution; protein-surface adsorption; protein-buffer interaction; analytical performance; Farmaceutisk kemi;

    Abstract : Proteins have such structural features that they may interact with different types of surfaces by all possible forces, i.e., electrostatic, hydrogen bonding, hydrophobic. In this thesis two different types of coatings for fused silica capillaries aimed to eliminate such interactions have been studied. READ MORE

  6. 9. Separation of Pharmaceuticals by Capillary Electrophoresis using Partial Filling and Multiple-injections

    Author : Henrik Lodén; Curt Pettersson; Torbjörn Arvidsson; Ahmad Amini; Morgan Stefansson; Uppsala universitet; []
    Keywords : Capillary Coating; Chiral Separation; Enantiomers; Mass-spectrometric Detection; Method Validation; Multiple-injection Capillary Zone Electrophoresis; Non-aqueous Capillary Electrophoresis; Organic Solvents; Pharmaceutical Analysis; Quantitative Analysis;

    Abstract : Different multiple-injection methodologies and the partial filling technique (PFT) have been utilized for separation of pharmaceuticals by capillary elec-trophoresis. In multiple-injection capillary zone electrophoresis (MICZE), the samples and all standards, used for construction of the calibration curve, are analyzed within a single run. READ MORE

  7. 10. Zwitterionic Separation Materials for Liquid Chromatography and Capillary Electrophoresis : Synthesis, Characterization and Application for Inorganic Ion and Biomolecule Separations

    Author : Wen Jiang; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Zwitterionic; stationary phase; separation; liquid chromatography; capillary electrophoresis; sulfobetaine; modification; covalently bonded; graft polymerization; ζ-potential; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : Liquid Chromatography (LC) and Capillary Electrophoresis (CE) are modern analytical techniques that play very important roles in many areas of modern science such as life science, biotechnology, biomedicine, environmental studies, and development of pharmaceutics. Even though these two techniques have existed and been subjected to studies for several decades, the developments of new separation materials for them are still very important till now in order to meet the different new demands for improvement from other disciplines in science. READ MORE