Search for dissertations about: "Caveola"

Showing result 1 - 5 of 6 swedish dissertations containing the word Caveola.

  2. 1. Integration of signalling in smooth muscle caveolae

    Author : Yulia Shakirova; Cellulär biomekanik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveola; caveolin; detrusor; cavin; smooth muscle contractility; remodelling; NO; vascular dysfunction; smooth muscle; erectile dysfunction;

    Abstract : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. READ MORE

  4. 2. A molecular approach to insulin signalling and caveolae in primary adipocytes

    Author : Karin Stenkula; Fredrik Nyström; Peter Strålfors; Peter Arner; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caveolae; insulin signalling; adipocytes; Medical cell biology; Medicinsk cellbiologi;

    Abstract : The prevalence of type II diabetes is increasing at an alarming rate due to the western world lifestyle. Type II diabetes is characterized by an insulin resistance distinguished by impaired glucose uptake in adipose and muscle tissues. READ MORE

  5. 3. Regulation of assembly and cell surface dynamics of caveolae

    Author : Jagan Mohan; Richard Lundmark; Oleg Shupliakov; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; medicinsk biokemi; Medical Biochemistry;

    Abstract : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. READ MORE

  6. 4. Caveolae in insulin signalling in human and rat adipocytes

    Author : Margareta Karlsson; Bengt Jergil; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The pancreatic hormone insulin is a key hormone in maintenance of metabolic homeostasis but it also exerts control on gene expression and cell growth. This thesis presents results on fhe role of caveolae in insulin signalling in human and rat adipocytes. READ MORE

  7. 5. Exploring novel roles of tumor pericytes

    Author : Jong Wook Hong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor biology has been extensively studied over the last few decades, with a principal focus on how neoplastic cells obtain cellular immortality. A number of oncogenes and tumor suppressor genes have been uncovered that regulate cancerous transformation. READ MORE